Full Product Name
ABR Antibody
Product Synonym Names
MDB
Product Gene Name
anti-ABR antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q12979
Specificity
The antibody detects endogenous levels of total ABR protein.
Purity/Purification
Antigen affinity purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.5mg/ml (lot specific)
Immunogen
Synthetic peptide of human ABR
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-ABR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABR antibody
This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene.
Product Categories/Family for anti-ABR antibody
Total protein Ab
Applications Tested/Suitable for anti-ABR antibody
Immunohistochemistry (IHC)
Application Notes for anti-ABR antibody
Immunohistochemistry: 1: 20-100
Immunohistochemistry (IHC) of anti-ABR antibody
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ABR Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
NCBI/Uniprot data below describe general gene information for ABR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001083.2
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NCBI GenBank Nucleotide #
NM_001092.4
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UniProt Primary Accession #
Q12979
[Other Products]
UniProt Secondary Accession #
Q13693; Q13694; B3KW89; B7Z6H7; D3DTH3; D3DTH4; F5H3S2; F5H8B3[Other Products]
UniProt Related Accession #
Q12979[Other Products]
Molecular Weight
92,425 Da
NCBI Official Full Name
active breakpoint cluster region-related protein isoform b
NCBI Official Synonym Full Names
active BCR-related
NCBI Official Symbol
ABR??[Similar Products]
NCBI Official Synonym Symbols
MDB
??[Similar Products]
NCBI Protein Information
active breakpoint cluster region-related protein
UniProt Protein Name
Active breakpoint cluster region-related protein
UniProt Gene Name
ABR??[Similar Products]
UniProt Entry Name
ABR_HUMAN
NCBI Summary for ABR
This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Feb 2012]
UniProt Comments for ABR
GTPase-activating protein for RAC and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them.
Research Articles on ABR
1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
