Product Name
GPR7, Polyclonal Antibody
Popular Item
Full Product Name
GPR7 Antibody
Product Synonym Names
G protein coupled receptor 7; g protein coupled receptor gpr7; G-protein coupled receptor 7; GPR7; MGC129755; Neuropeptides B and W receptor 1; Neuropeptides B/W receptor 1; Neuropeptides B/W receptor type 1; NPB and NPW receptor 1; NPBW1_HUMAN; NPBWR1; opioid somatostatin like receptor 7
Product Gene Name
anti-GPR7 antibody
[Similar Products]
Product Synonym Gene Name
NPBWR1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P48145
Specificity
GPR7 antibody detects endogenous levels of total GPR7
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide
Subcellular Location
Plasma Membrane
Tissue Specificity
Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.
Predicted Cross Reactivity
Pig, Bovine, Sheep
Similarity
Pig (83%), Bovine (83%), Sheep (83%)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-GPR7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GPR7 antibody
Function: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
Similarity: Belongs to the G-protein coupled receptor 1 family.
Applications Tested/Suitable for anti-GPR7 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-GPR7 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
Western Blot (WB) of anti-GPR7 antibody
Western blot analysis of GPR7 expression in Human fetal brain lysate ;, The lane on the left is treated with the antigen-specific peptide.
Immunohistochemistry (IHC) of anti-GPR7 antibody
MBS9604274 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
NCBI/Uniprot data below describe general gene information for GPR7. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005276.2
[Other Products]
NCBI GenBank Nucleotide #
NM_005285.3
[Other Products]
UniProt Primary Accession #
P48145
[Other Products]
UniProt Secondary Accession #
Q6NTC7[Other Products]
UniProt Related Accession #
P48145[Other Products]
Molecular Weight
Observed: 36 kDa
Predicted: 37 kDa
NCBI Official Full Name
neuropeptides B/W receptor type 1
NCBI Official Synonym Full Names
neuropeptides B and W receptor 1
NCBI Official Symbol
NPBWR1??[Similar Products]
NCBI Official Synonym Symbols
GPR7
??[Similar Products]
NCBI Protein Information
neuropeptides B/W receptor type 1
UniProt Protein Name
Neuropeptides B/W receptor type 1
UniProt Synonym Protein Names
G-protein coupled receptor 7
UniProt Gene Name
NPBWR1??[Similar Products]
UniProt Synonym Gene Names
GPR7??[Similar Products]
UniProt Comments for GPR7
Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.
Research Articles on GPR7
1. screening of GPR7 gene mutations among lean and obese subjects revealed a Tyr135Phe allelic variant that is fairly common in the study population. This variant is unlikely to cause a functional derangement of the receptor
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
