Full Product Name
HCRTR2 Antibody
Product Synonym Names
OX2R
Product Gene Name
anti-HCRTR2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O43614
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity purification
Immunogen
A synthetic peptide of human HCRTR2
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-HCRTR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HCRTR2 antibody
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A.
Product Categories/Family for anti-HCRTR2 antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Applications Tested/Suitable for anti-HCRTR2 antibody
Western Blot (WB)
Application Notes for anti-HCRTR2 antibody
WB: 1:500-1:2000
Western Blot (WB) of anti-HCRTR2 antibody
Western blot analysis of extracts of mouse heartcellline, using HCRTR2 antibody.
NCBI/Uniprot data below describe general gene information for HCRTR2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001517.2
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NCBI GenBank Nucleotide #
NM_001526.4
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UniProt Primary Accession #
O43614
[Other Products]
UniProt Secondary Accession #
Q5VTM0[Other Products]
UniProt Related Accession #
O43614[Other Products]
NCBI Official Full Name
orexin receptor type 2
NCBI Official Synonym Full Names
hypocretin receptor 2
NCBI Official Symbol
HCRTR2??[Similar Products]
NCBI Official Synonym Symbols
OX2R
??[Similar Products]
NCBI Protein Information
orexin receptor type 2
UniProt Protein Name
Orexin receptor type 2
UniProt Synonym Protein Names
Hypocretin receptor type 2
Protein Family
Orexin receptor
UniProt Gene Name
HCRTR2??[Similar Products]
UniProt Synonym Gene Names
Ox-2-R; Ox2-R; Ox2R??[Similar Products]
NCBI Summary for HCRTR2
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]
UniProt Comments for HCRTR2
Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca2+ levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).
Research Articles on HCRTR2
1. The present study demonstrated that aa residues in the C-terminus serve an important role in the expression and signal transduction of OX2R. In addition, the aa residues in different locations possess evidentially different roles.
Precautions
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Disclaimer
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