Product Name
Neuropeptides B/W receptor type 1 (NPBWR1), Recombinant Protein
Full Product Name
Recombinant Human Neuropeptides B/W receptor type 1 (NPBWR1)
Product Gene Name
NPBWR1 recombinant protein
[Similar Products]
Product Synonym Gene Name
GPR7[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-328aa; Full length protein
Sequence
MDNASFSEPW PANASGPDPA LSCSNASTLA PLPAPLAVAV PVVYAVICAV GLAGNSAVLY VLLRAPRMKT VTNLFILNLA IADELFTLVL PINIADFLLR QWPFGELMCK LIVAIDQYNT FSSLYFLTVM SADRYLVVLA TAESRRVAGR TYSAARAVSL AVWGIVTLVV LPFAVFARLD DEQGRRQCVL VFPQPEAFWW RASRLYTLVL GFAIPVSTIC VLYTTLLCRL HAMRLDSHAK ALERAKKRVT FLVVAILAVC LLCWTPYHLS TVVALTTDLP QTPLVIAISY FITSLSYANS CLNPFLYAFL DASFRRNLRQ LITCRAAA
3D Structure
ModBase 3D Structure for P48145
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of NPBWR1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for NPBWR1 recombinant protein
Transmembrane Protein
Application Notes for NPBWR1 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for NPBWR1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005276.2
[Other Products]
NCBI GenBank Nucleotide #
NM_005285.3
[Other Products]
UniProt Primary Accession #
P48145
[Other Products]
UniProt Secondary Accession #
Q6NTC7[Other Products]
UniProt Related Accession #
P48145[Other Products]
Molecular Weight
36,103 Da
NCBI Official Full Name
neuropeptides B/W receptor type 1
NCBI Official Synonym Full Names
neuropeptides B/W receptor 1
NCBI Official Symbol
NPBWR1??[Similar Products]
NCBI Official Synonym Symbols
GPR7
??[Similar Products]
NCBI Protein Information
neuropeptides B/W receptor type 1
UniProt Protein Name
Neuropeptides B/W receptor type 1
UniProt Synonym Protein Names
G-protein coupled receptor 7
Protein Family
Neuropeptides B/W receptor
UniProt Gene Name
NPBWR1??[Similar Products]
UniProt Synonym Gene Names
GPR7??[Similar Products]
UniProt Entry Name
NPBW1_HUMAN
UniProt Comments for NPBWR1
NPBWR1: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1
Chromosomal Location of Human Ortholog: 8p22-q21.13
Cellular Component: integral to membrane; integral to plasma membrane; neuron projection; plasma membrane
Molecular Function: neuropeptide binding; neuropeptide receptor activity; opioid receptor activity; protein binding
Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; neuropeptide signaling pathway; regulation of metabolic process; synaptic transmission
Research Articles on NPBWR1
1. screening of GPR7 gene mutations among lean and obese subjects revealed a Tyr135Phe allelic variant that is fairly common in the study population. This variant is unlikely to cause a functional derangement of the receptor
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
