Full Product Name
HCRTR2 Antibody
Product Gene Name
anti-HCRTR2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O43614
Species Reactivity
Human, Mouse, Rat
Concentration
1.0mg/ml (lot specific)
Other Notes
Small volumes of anti-HCRTR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-HCRTR2 antibody
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for HCRTR2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001517.2
[Other Products]
NCBI GenBank Nucleotide #
NM_001526.4
[Other Products]
UniProt Primary Accession #
O43614
[Other Products]
UniProt Secondary Accession #
Q5VTM0[Other Products]
UniProt Related Accession #
O43614[Other Products]
Molecular Weight
50,694 Da
NCBI Official Full Name
orexin receptor type 2
NCBI Official Synonym Full Names
hypocretin receptor 2
NCBI Official Symbol
HCRTR2??[Similar Products]
NCBI Official Synonym Symbols
OX2R
??[Similar Products]
NCBI Protein Information
orexin receptor type 2
UniProt Protein Name
Orexin receptor type 2
UniProt Synonym Protein Names
Hypocretin receptor type 2
Protein Family
Orexin receptor
UniProt Gene Name
HCRTR2??[Similar Products]
UniProt Synonym Gene Names
Ox-2-R; Ox2-R; Ox2R??[Similar Products]
NCBI Summary for HCRTR2
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]
UniProt Comments for HCRTR2
HCRTR2: Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 6p12.1
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: neuropeptide receptor activity; orexin receptor activity; peptide binding
Biological Process: cellular response to hormone stimulus; cytosolic calcium ion homeostasis; neuropeptide signaling pathway; regulation of circadian sleep/wake cycle, sleep; synaptic transmission
Research Articles on HCRTR2
1. Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation is highly unlikely to be caused by mutations in the exons of the HCRTR2 gene.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
