Product Name
NPBWR1, Polyclonal Antibody
Full Product Name
NPBWR1 Antibody - N-terminal region
Product Gene Name
anti-NPBWR1 antibody
[Similar Products]
Product Synonym Gene Name
GPR7; MGC129755[Similar Products]
Antibody/Peptide Pairs
NPBWR1 peptide (MBS3241473) is used for blocking the activity of NPBWR1 antibody (MBS3216574)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: FSEPWPANAS GPDPALSCSN ASTLAPLPAP LAVAVPVVYA VICAVGLAGN
3D Structure
ModBase 3D Structure for P48145
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human NPBWR1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-NPBWR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-NPBWR1 antibody
This is a rabbit polyclonal antibody against NPBWR1. It was validated on Western Blot
Target Description: NPBWR1 interacts specifically with a number of opioid ligands. NPBWR1 is a receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. NPBWR1 has a higher affinity for neuropeptide B.
Product Categories/Family for anti-NPBWR1 antibody
Polyclonal; Signaling Intermediate;
Applications Tested/Suitable for anti-NPBWR1 antibody
Western Blot (WB)
Western Blot (WB) of anti-NPBWR1 antibody
WB Suggested Anti-NPBWR1 Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal Brain
NCBI/Uniprot data below describe general gene information for NPBWR1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005276
[Other Products]
NCBI GenBank Nucleotide #
NM_005285
[Other Products]
UniProt Primary Accession #
P48145
[Other Products]
UniProt Related Accession #
P48145[Other Products]
NCBI Official Full Name
neuropeptides B/W receptor type 1
NCBI Official Synonym Full Names
neuropeptides B and W receptor 1
NCBI Official Symbol
NPBWR1??[Similar Products]
NCBI Official Synonym Symbols
GPR7
??[Similar Products]
NCBI Protein Information
neuropeptides B/W receptor type 1
UniProt Protein Name
Neuropeptides B/W receptor type 1
UniProt Synonym Protein Names
G-protein coupled receptor 7
Protein Family
Neuropeptides B/W receptor
UniProt Gene Name
NPBWR1??[Similar Products]
UniProt Synonym Gene Names
GPR7??[Similar Products]
UniProt Entry Name
NPBW1_HUMAN
UniProt Comments for NPBWR1
NPBWR1: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR
Chromosomal Location of Human Ortholog: 8p22-q21.13
Cellular Component: neuron projection; integral to plasma membrane; plasma membrane; integral to membrane
Molecular Function: neuropeptide binding; protein binding; neuropeptide receptor activity; opioid receptor activity
Biological Process: synaptic transmission; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; neuropeptide signaling pathway; regulation of metabolic process
Research Articles on NPBWR1
1. screening of GPR7 gene mutations among lean and obese subjects revealed a Tyr135Phe allelic variant that is fairly common in the study population. This variant is unlikely to cause a functional derangement of the receptor
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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