Neuropeptides B/W receptor type 1; G-protein coupled receptor 7; NPBWR1; GPR7

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit Ig

Rabbit

This NPBWR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-250 amino acids from the C-terminal region of human NPBWR1.

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Vial Concentration: 0.5 (lot specific)

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Small volumes of anti-NPBWR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

NPBWR1 interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.

Neuroscience; Signal Transduction; GPCR Antibodies

Western Blot (WB), ELISA (EIA)

WB~~1:1000

NPBWR1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the NPBWR1 Antibody detected the NPBWR1 protein (arrow).

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neuropeptides B/W receptor 1

neuropeptides B/W receptor type 1

Neuropeptides B/W receptor type 1

GPR7??[Similar Products]

NPBW1_HUMAN

NPBWR1: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p22-q21.13

Cellular Component: neuron projection; integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: neuropeptide binding; neuropeptide receptor activity; protein binding; opioid receptor activity

Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor protein signaling pathway; synaptic transmission; neuropeptide signaling pathway; regulation of metabolic process

Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)
Lambert, N.A. Sci Signal 1 (25), RE5 (2008) :
Cottrell, S., et al. J. Urol. 177(5):1753-1758(2007)
Mazzocchi, G., et al. J. Clin. Endocrinol. Metab. 90(6):3466-3471(2005)
Zaratin, P.F., et al. Mol. Cell. Neurosci. 28(1):55-63(2005)

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