Product Name
(Rhesus macaque) Tubulin beta chain (TUBB), Recombinant Protein
Popular Item
Full Product Name
Recombinant Macaca mulatta (Rhesus macaque) Tubulin beta chain (TUBB)
Product Synonym Names
Recombinant (Rhesus macaque) Tubulin beta chain (TUBB); Tubulin beta chain; Tubulin beta-5 chain
Product Gene Name
TUBB recombinant protein
[Similar Products]
Product Synonym Gene Name
TUBB; TUBB5[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-444aa; Full length protein
Sequence
MREIVHIQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLDRISVY YNEATGGKYV PRAILVDLEP GTMDSVRSGP FGQIFRPDNF VFGQSGAGNN WAKGHYTEGA ELVDSVLDVV RKEAESCDCL QGFQLTHSLG GGTGSGMGTL LISKIREEYP DRIMNTFSVV PSPKVSDTVV EPYNATLSVH QLVENTDETY CIDNEALYDI CFRTLKLTTP TYGDLNHLVS ATMSGVTTCL RFPGQLNADL RKLAVNMVPF PRLHFFMPGF APLTSRGSQQ YRALTVPELT QQVFDAKNMM AACDPRHGRY LTVAAVFRGR MSMKEVDEQM LNVQNKNSSY FVEWIPNNVK TAVCDIPPRG LKMAVTFIGN STAIQELFKR ISEQFTAMFR RKAFLHWYTG EGMDEMEFTE AESNMNDLVS EYQQYQDATA EEEEDFGEEA EEEA
Chromosome Location
Chromosome: 4; NC_007861.1 (30304964..30309107). Location: chromosome: 4
3D Structure
ModBase 3D Structure for P69895
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Macaca mulatta (Rhesus macaque)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of TUBB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for TUBB. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001027985.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001032813.1
[Other Products]
UniProt Primary Accession #
P69895
[Other Products]
UniProt Secondary Accession #
P05218; Q8WUC1; Q9CY33[Other Products]
UniProt Related Accession #
P69895[Other Products]
Molecular Weight
49,671 Da[Similar Products]
NCBI Official Full Name
tubulin beta chain
NCBI Official Symbol
TUBB??[Similar Products]
NCBI Official Synonym Symbols
TUBB5; TUBB2A; TUBB2B
??[Similar Products]
NCBI Protein Information
tubulin beta chain; tubulin beta-5 chain; tubulin beta-2B chain; tubulin, beta 2A class IIa
UniProt Protein Name
Tubulin beta chain
UniProt Synonym Protein Names
Tubulin beta-5 chain
UniProt Gene Name
TUBB??[Similar Products]
UniProt Synonym Gene Names
TUBB5??[Similar Products]
UniProt Entry Name
TBB5_MACMU
UniProt Comments for TUBB
Function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
Subunit structure: Dimer of alpha and beta chains. May interact with RNABP10
By similarity. Interacts with PIFO
By similarity.
Subcellular location: Cytoplasm ? cytoskeleton.
Tissue specificity: Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Post-translational modification: Some glutamate residues at the C-terminus are either polyglutamylated or polyglycylated. These 2 modifications occur exclusively on glutamate residues and result in either polyglutamate or polyglycine chains on the gamma-carboxyl group. Glycylation is mainly limited to tubulin incorporated into axonemes (cilia and flagella) whereas glutamylation is prevalent in neuronal cells, centrioles, axonemes, and the mitotic spindle. Both modifications can coexist on the same protein on adjacent residues, and lowering polyglycylation levels increases polyglutamylation, and reciprocally. The precise function of such modifications is still unclear but they are regulate the assembly and dynamics of axonemal microtubules
By similarity.
Sequence similarities: Belongs to the tubulin family.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
