Rat 6-pyruvoyl tetrahydrobiopterin synthase (PTS) ELISA kit; FLJ97081; PTPS; 6-pyruvoyl tetrahydrobiopterin synthase; PTP synthase; 6-pyruvoyltetrahydropterin synthase

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of PTS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9340441 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 6-pyruvoyltetrahydropterin synthase (PTS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PTS. The ELISA analytical biochemical technique of the MBS9340441 kit is based on PTS antibody-PTS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

16,241 Da

6-pyruvoyl-tetrahydropterin synthase

6-pyruvoyl tetrahydrobiopterin synthase; PTPS; PTP synthase; 6-pyruvoyltetrahydropterin synthase

6-pyruvoyl tetrahydrobiopterin synthase

PTP synthase; PTPS??[Similar Products]

PTPS_RAT

catalyzes the formation of 6-pyruvoyltetrahydrobiopterin in tetrahydrobiopterin biosynthesis [RGD, Feb 2006]

PTS: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6- pyruvoyl tetrahydropterin. Defects in PTS are the cause of BH4-deficient hyperphenylalaninemia type A (HPABH4A); also called 6-pyruvoyl-tetrahydropterin synthase deficiency (PTS deficiency) or hyperphenylalaninemia tetrahydrobiopterin-deficient due to PTS deficiency. HPABH4A is an autosomal recessive disorder characterized by depletion of the neurotransmitters dopamine and serotonin, and clinically by severe neurological symptoms unresponsive to the classic phenylalanine-low diet. Belongs to the PTPS family.

Protein type: Cofactor and Vitamin Metabolism - folate biosynthesis; Mitochondrial; Lyase; EC 4.2.3.12

Cellular Component: mitochondrion; cytoplasm

Molecular Function: identical protein binding; protein homodimerization activity; metal ion binding; 6-pyruvoyltetrahydropterin synthase activity

Biological Process: tetrahydrobiopterin biosynthetic process

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