Product Name
U4/U6 small nuclear ribonucleoprotein Prp31 (PRPF31), Recombinant Protein
Full Product Name
Recombinant Human U4/U6 small nuclear ribonucleoprotein Prp31 (PRPF31)
Product Gene Name
PRPF31 recombinant protein
[Similar Products]
Product Synonym Gene Name
PRPF31[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-499aa, full length protein
Sequence
MSLADELLAD LEEAAEEEEG GSYGEEEEEP AIEDVQEETQ LDLSGDSVKT IAKLWDSKMF AEIMMKIEEY ISKQAKASEV MGPVEAAPEY RVIVDANNLT VEIENELNII HKFIRDKYSK RFPELESLVP NALDYIRTVK ELGNSLDKCK NNENLQQILT NATIMVVSVT ASTTQGQQLS EEELERLEEA CDMALELNAS KHRIYEYVES RMSFIAPNLS IIIGASTAAK IMGVAGGLTN LSKMPACNIM LLGAQRKTLS GFSSTSVLPH TGYIYHSDIV QSLPPDLRRK AARLVAAKCT LAARVDSFHE STEGKVGYEL KDEIERKFDK WQEPPPVKQV KPLPAPLDGQ RKKRGGRRYR KMKERLGLTE IRKQANRMSF GEIEEDAYQE DLGFSLGHLG KSGSGRVRQT QVNEATKARI SKTLQRTLQK QSVVYGGKST IRDRSSGTAS SVAFTPLQGL EIVNPQAAEK KVAEANQKYF SSMAEFLKVK GEKSGLMST
3D Structure
ModBase 3D Structure for Q8WWY3
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of PRPF31 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for PRPF31. It may not necessarily be applicable to this product.
NCBI Accession #
NP_056444.3
[Other Products]
NCBI GenBank Nucleotide #
NM_015629.3
[Other Products]
UniProt Primary Accession #
Q8WWY3
[Other Products]
UniProt Secondary Accession #
Q17RB4; Q8N7F9; Q9H271; Q9Y439; E7ESA8; F1T0A4; F1T0A5[Other Products]
UniProt Related Accession #
Q8WWY3[Other Products]
Molecular Weight
54,909 Da
NCBI Official Full Name
U4/U6 small nuclear ribonucleoprotein Prp31
NCBI Official Synonym Full Names
pre-mRNA processing factor 31
NCBI Official Symbol
PRPF31??[Similar Products]
NCBI Official Synonym Symbols
RP11; PRP31; SNRNP61; NY-BR-99
??[Similar Products]
NCBI Protein Information
U4/U6 small nuclear ribonucleoprotein Prp31
UniProt Protein Name
U4/U6 small nuclear ribonucleoprotein Prp31
UniProt Synonym Protein Names
Pre-mRNA-processing factor 31; Serologically defined breast cancer antigen NY-BR-99; U4/U6 snRNP 61 kDa protein; Protein 61K; hPrp31
Protein Family
U4/U6 small nuclear ribonucleoprotein
UniProt Gene Name
PRPF31??[Similar Products]
UniProt Synonym Gene Names
PRP31; Protein 61K; hPrp31??[Similar Products]
NCBI Summary for PRPF31
This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.[provided by RefSeq, Jan 2009]
UniProt Comments for PRPF31
Involved in pre-mRNA splicing. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.
Research Articles on PRPF31
1. we identified the
biological function of lncRNA RP11-838N2.4 in temolozomide resistance in glioblastoma
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
