Product Name
Filamin-B (Flnb), Recombinant Protein
Full Product Name
Recombinant Mouse Filamin-B (Flnb) , partial
Product Gene Name
Flnb recombinant protein
[Similar Products]
Product Synonym Gene Name
Flnb[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q80X90
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Flnb recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Flnb recombinant protein
This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
NCBI/Uniprot data below describe general gene information for Flnb. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001074896.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001081427.1
[Other Products]
UniProt Primary Accession #
Q80X90
[Other Products]
UniProt Secondary Accession #
Q8VHX4; Q8VHX7; Q99KY3; E9QNV9[Other Products]
UniProt Related Accession #
Q80X90[Other Products]
Molecular Weight
277,825 Da
NCBI Official Full Name
filamin-B isoform a
NCBI Official Synonym Full Names
filamin, beta
NCBI Official Symbol
Flnb??[Similar Products]
NCBI Official Synonym Symbols
Fln-b; AL024016
??[Similar Products]
NCBI Protein Information
filamin-B
UniProt Protein Name
Filamin-B
UniProt Synonym Protein Names
ABP-280-like protein; Actin-binding-like protein; Beta-filamin
UniProt Gene Name
Flnb??[Similar Products]
UniProt Synonym Gene Names
FLN-B??[Similar Products]
UniProt Comments for Flnb
Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton ().
Research Articles on Flnb
1. These findings indicate that FLNB is involved in attenuation of TGFb/BMP signaling and influences annulus fibrosus cell fate
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
