Product Name
CD295 (LEPR), ELISA Kit
Full Product Name
Mouse CD295 ELISA Kit
Product Synonym Names
DB; OBR; Leptin receptor; LEP-R; HuB219; OB receptor; OB-R; CD295
Product Gene Name
LEPR elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sample Manual Insert
Download Sample PDF Manual View Sample PDF Manual
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for P48356
Samples
Cell Culture Supernatants, Serum, Plasma
Detection Range
156 pg/ml - 10000 pg/ml
Detection Method
Colorimetric
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of LEPR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for LEPR purchase
MBS825084 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the CD295 (LEPR) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LEPR. The ELISA analytical biochemical technique of the MBS825084 kit is based on LEPR antibody-LEPR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LEPR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LEPR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
LEPR elisa kit
Sandwich ELISA for quantitative detection of Mouse CD295 concentrations.
Applications Tested/Suitable for LEPR elisa kit
Sandwich ELISA (SE)
Typical Testing Data/Standard Curve (for reference only) of LEPR elisa kit
NCBI/Uniprot data below describe general gene information for LEPR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001116371.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001122899.1
[Other Products]
UniProt Primary Accession #
P48356
[Other Products]
UniProt Secondary Accession #
O35686; O54986; Q61215; Q64309; Q9QWG3; Q9QWV5[Other Products]
UniProt Related Accession #
P48356[Other Products]
Molecular Weight
90,887 Da
NCBI Official Full Name
leptin receptor isoform 3
NCBI Official Synonym Full Names
leptin receptor
NCBI Official Symbol
Lepr??[Similar Products]
NCBI Official Synonym Symbols
db; Obr; obl; Leprb; Modb1; LEPROT; OB-RGRP; diabetes; obese-like
??[Similar Products]
NCBI Protein Information
leptin receptor; B219; LEP-R; OB receptor; leptin receptor gene-related protein
UniProt Protein Name
Leptin receptor
UniProt Synonym Protein Names
B219; OB receptor; OB-R; CD_antigen: CD295
Protein Family
Leptin receptor
UniProt Gene Name
Lepr??[Similar Products]
UniProt Synonym Gene Names
Db; Obr; LEP-R; OB-R??[Similar Products]
UniProt Entry Name
LEPR_MOUSE
UniProt Comments for LEPR
LEPR: the receptor for leptin (obesity factor). A single-transmembrane-domain receptor of the cytokine receptor family. On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Five alternatively spliced transcript variants have been reported.
Protein type: Receptor, cytokine; Membrane protein, integral
Cellular Component: extracellular space; membrane; integral to plasma membrane; integral to membrane; extracellular region; plasma membrane; receptor complex
Molecular Function: identical protein binding; hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; transmembrane receptor activity; peptide hormone binding; protein-hormone receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; cholesterol metabolic process; positive regulation of MAPKKK cascade; eating behavior; negative regulation of hydrolase activity; negative regulation of gluconeogenesis; regulation of metabolic process; angiogenesis; signal transduction; leptin-mediated signaling pathway
Research Articles on LEPR
1. Obese diabetic mice lacking leptin receptor (db/db) are deficient in postnatal regenerative osteogenesis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.