Product Name
Limb region 1 protein homolog (LMBR1), Recombinant Protein
Full Product Name
Recombinant Human Limb region 1 protein homolog (LMBR1), partial
Product Gene Name
LMBR1 recombinant protein
[Similar Products]
Product Synonym Gene Name
LMBR1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8WVP7
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of LMBR1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for LMBR1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_071903.2
[Other Products]
NCBI GenBank Nucleotide #
NM_022458.3
[Other Products]
UniProt Primary Accession #
Q8WVP7
[Other Products]
UniProt Secondary Accession #
Q8N3E3; Q96QZ5; Q9H5N0; Q9HAG9; Q9UDN5; Q9Y6U2; A4D242[Other Products]
UniProt Related Accession #
Q8WVP7[Other Products]
Molecular Weight
59,458 Da
NCBI Official Full Name
limb region 1 protein homolog isoform b
NCBI Official Synonym Full Names
limb development membrane protein 1
NCBI Official Symbol
LMBR1??[Similar Products]
NCBI Official Synonym Symbols
LSS; TPT; ZRS; ACHP; PPD2; THYP; DIF14; C7orf2
??[Similar Products]
NCBI Protein Information
limb region 1 protein homolog
UniProt Protein Name
Limb region 1 protein homolog
UniProt Synonym Protein Names
Differentiation-related gene 14 protein
Protein Family
Limb region 1 protein
UniProt Gene Name
LMBR1??[Similar Products]
UniProt Synonym Gene Names
C7orf2; DIF14??[Similar Products]
NCBI Summary for LMBR1
This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq, Jul 2008]
UniProt Comments for LMBR1
Putative membrane receptor.
Research Articles on LMBR1
1. These include a patient with hypoplastic phalanges and absent hallux bilaterally with de novo deletion of 11.9 Mb on 7p21.1-22.1 spanning 63 genes including RAC1, another patient with severe Holt-Oram syndrome and a large de novo deletion 2.2 Mb on 12q24.13-24.21 spanning 20 genes including TBX3 and TBX5, and a third patient with acheiropodia who had a nullizygous deletion of 102 kb on 7q36.3 spanning LMBR1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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