Product Name
HB9/HLXB9, Polyclonal Antibody
Full Product Name
Anti-HB9/HLXB9 Rabbit pAb
Product Synonym Names
HB9; HLXB9; Homeobox HB9; Homeobox protein HB9; HOXHB9; MNX1; Motor neuron and pancreas homeobox protein 1; SCRA1
Product Gene Name
anti-HB9/HLXB9 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P50219
Species Reactivity
Human, Mouse
Specificity
HB9/HLXB9 Antibody detects endogenous levels of total HB9/HLXB9
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
A synthesized peptide derived from human HB9/HLXB9
Subcellular Location
Nucleus
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Other Notes
Small volumes of anti-HB9/HLXB9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-HB9/HLXB9 antibody
Putative transcription factor involved in pancreas development and function.
Applications Tested/Suitable for anti-HB9/HLXB9 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-HB9/HLXB9 antibody
WB: 1:500-1:2000
IP: 1:50
Western Blot (WB) of anti-HB9/HLXB9 antibody
Western blot analysis of HB9/HLXB9 expression in Molt-4 cell lysate.
NCBI/Uniprot data below describe general gene information for HB9/HLXB9. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001158727.1
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NCBI GenBank Nucleotide #
NM_001165255.1
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UniProt Primary Accession #
P50219
[Other Products]
UniProt Secondary Accession #
Q9Y648; F5H401[Other Products]
UniProt Related Accession #
P50219[Other Products]
NCBI Official Full Name
motor neuron and pancreas homeobox protein 1 isoform 2
NCBI Official Synonym Full Names
motor neuron and pancreas homeobox 1
NCBI Official Symbol
MNX1??[Similar Products]
NCBI Official Synonym Symbols
HB9; HLXB9; SCRA1; HOXHB9
??[Similar Products]
NCBI Protein Information
motor neuron and pancreas homeobox protein 1
UniProt Protein Name
Motor neuron and pancreas homeobox protein 1
UniProt Synonym Protein Names
Homeobox protein HB9
UniProt Gene Name
MNX1??[Similar Products]
UniProt Synonym Gene Names
HLXB9??[Similar Products]
NCBI Summary for HB9/HLXB9
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
UniProt Comments for HB9/HLXB9
Putative transcription factor involved in pancreas development and function.
Research Articles on HB9/HLXB9
1. Findings identify RGS12 as a candidate tumor-suppressor gene in AA prostate cancer, which acts by decreasing expression of AKT and MNX1, establishing a novel oncogenic axis in this disparate disease setting.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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