Full Product Name
Anti-PAH Antibody (C-Terminus)
Product Synonym Names
Rabbit Polyclonal (IgG)
Product Gene Name
anti-PAH antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Mouse, Bovine, Human
Specificity
Recognizes endogenous levels of PAH protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, pH 7.3, 0.01% sodium azide, 30% glycerol.
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-terminal region of human PAH.
Preparation and Storage
Store at -20 degree C.
Aliquot to avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-PAH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PAH antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-PAH antibody
IHC-P: 1:100
WB: 1:500-1:1000
Immunohistochemistry (IHC) of anti-PAH antibody
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry (WB) of anti-PAH antibody
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western Blot (WB) of anti-PAH antibody
Western blot analysis of PAH expression in HepG2 (A); mouse liver (B) whole cell lysates.
NCBI/Uniprot data below describe general gene information for PAH. It may not necessarily be applicable to this product.
NCBI Accession #
AAA80910.1
[Other Products]
UniProt Secondary Accession #
Q16717; Q8TC14[Other Products]
UniProt Related Accession #
P00439[Other Products]
Molecular Weight
51,862 Da
NCBI Official Full Name
PAH
NCBI Official Synonym Full Names
phenylalanine hydroxylase
NCBI Official Symbol
PAH??[Similar Products]
NCBI Official Synonym Symbols
PH; PKU; PKU1
??[Similar Products]
NCBI Protein Information
phenylalanine-4-hydroxylase
UniProt Protein Name
Phenylalanine-4-hydroxylase
UniProt Synonym Protein Names
Phe-4-monooxygenase
Protein Family
Phenylalanine-4-hydroxylase
UniProt Gene Name
PAH??[Similar Products]
UniProt Synonym Gene Names
PAH??[Similar Products]
NCBI Summary for PAH
This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. [provided by RefSeq, Aug 2017]
Research Articles on PAH
1. Among phenylketonuria patients, some with autism at the time of evaluation, six mutations were identified: p.E280K, p.G352Vfs, IVS10nt11, p.I224T, p.R261Q, and p.R252W. Study found no correlation between autism and mutations affecting the phenylalanine hydroxylase gene, but the age of die
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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