Product Name
Coiled-coil domain-containing protein 6 (CCDC6), Recombinant Protein
Full Product Name
Recombinant Human Coiled-coil domain-containing protein 6 (CCDC6)
Product Gene Name
CCDC6 recombinant protein
[Similar Products]
Product Synonym Gene Name
CCDC6[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-474aa, Full Length of Mature Protein
Sequence
ADSASESDTD GAGGNSSSSA AMQSSCSSTS GGGGGGGGGG GGGKSGGIVI SPFRLEELTN RLASLQQENK VLKIELETYK LKCKALQEEN RDLRKASVTI QARAEQEEEF ISNTLFKKIQ ALQKEKETLA VNYEKEEEFL TNELSRKLMQ LQHEKAELEQ HLEQEQEFQV NKLMKKIKKL ENDTISKQLT LEQLRREKID LENTLEQEQE ALVNRLWKRM DKLEAEKRIL QEKLDQPVSA PPSPRDISME IDSPENMMRH IRFLKNEVER LKKQLRAAQL QHSEKMAQYL EEERHMREEN LRLQRKLQRE MERREALCRQ LSESESSLEM DDERYFNEMS AQGLRPRTVS SPIPYTPSPS SSRPISPGLS YASHTVGFTP PTSLTRAGMS YYNSPGLHVQ HMGTSHGITR PSPRRSNSPD KFKRPTPPPS PNTQTPVQPP PPPPPPPMQP TVPSAATSQP TPSQHSAHPS SQP
3D Structure
ModBase 3D Structure for Q16204
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CCDC6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CCDC6. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005427.2
[Other Products]
NCBI GenBank Nucleotide #
NM_005436.4
[Other Products]
UniProt Primary Accession #
Q16204
[Other Products]
UniProt Secondary Accession #
Q15250; Q6GSG7[Other Products]
UniProt Related Accession #
Q16204[Other Products]
Molecular Weight
53,291 Da
NCBI Official Full Name
coiled-coil domain-containing protein 6
NCBI Official Synonym Full Names
coiled-coil domain containing 6
NCBI Official Symbol
CCDC6??[Similar Products]
NCBI Official Synonym Symbols
H4; PTC; TPC; TST1; D10S170
??[Similar Products]
NCBI Protein Information
coiled-coil domain-containing protein 6
UniProt Protein Name
Coiled-coil domain-containing protein 6
UniProt Synonym Protein Names
Papillary thyroid carcinoma-encoded protein; Protein H4
Protein Family
Coiled-coil domain-containing protein
UniProt Gene Name
CCDC6??[Similar Products]
UniProt Synonym Gene Names
D10S170; TST1??[Similar Products]
NCBI Summary for CCDC6
This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.[provided by RefSeq, Sep 2010]
Research Articles on CCDC6
1. FGFR inhibitors, particularly BGJ398, are therapeutic options for cholangiocarcinoma patients harboring FGFR2-CCDC6 fusions.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
