Product Name
MNX1, Polyclonal Antibody
Popular Item
Full Product Name
MNX1 Antibody
Product Synonym Names
HB 9; HB9; HLXB 9; HLXB9; Homeo box HB9; Homeobox HB9; Homeobox protein HB9; HOXHB9; MNX1; MNX1_HUMAN; Motor neuron and pancreas homeobox 1; Motor neuron and pancreas homeobox protein 1; Sacral agenesis autosomal dominant (Currarino triad); SCRA 1; SCRA1
Product Gene Name
anti-MNX1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P50219
Species Reactivity
Human, Mouse, Rat
Specificity
MNX1 antibody detects endogenous levels of total MNX1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
A synthesized peptide derived from human MNX1
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in lymphoid and pancreatic tissues.
Predicted Cross Reactivity
Zebrafish, Bovine, Dog
Similarity
Zebrafish (86%), Bovine (82%), Dog (91%)
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Other Notes
Small volumes of anti-MNX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MNX1 antibody
Function: Putative transcription factor involved in pancreas development and function.
Applications Tested/Suitable for anti-MNX1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-MNX1 antibody
WB: 1:1000-3000
Western Blot (WB) of anti-MNX1 antibody
Western blot analysis of MNX1 using LOVO whole lysates.

NCBI/Uniprot data below describe general gene information for MNX1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001158727.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001165255.1
[Other Products]
UniProt Primary Accession #
P50219
[Other Products]
UniProt Secondary Accession #
Q9Y648; F5H401[Other Products]
UniProt Related Accession #
P50219[Other Products]
Molecular Weight
Observed: 41 kDa
Predicted: 41 kDa
NCBI Official Full Name
motor neuron and pancreas homeobox protein 1 isoform 2
NCBI Official Synonym Full Names
motor neuron and pancreas homeobox 1
NCBI Official Symbol
MNX1??[Similar Products]
NCBI Official Synonym Symbols
HB9; HLXB9; SCRA1; HOXHB9
??[Similar Products]
NCBI Protein Information
motor neuron and pancreas homeobox protein 1
UniProt Protein Name
Motor neuron and pancreas homeobox protein 1
UniProt Synonym Protein Names
Homeobox protein HB9
Protein Family
Motor neuron and pancreas homeobox protein
UniProt Gene Name
MNX1??[Similar Products]
UniProt Synonym Gene Names
HLXB9??[Similar Products]
NCBI Summary for MNX1
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
UniProt Comments for MNX1
Putative transcription factor involved in pancreas development and function.
Research Articles on MNX1
1. Pathogenic variants in MNX1 were detected in 28% of all CS cases and 25% of sporadic cases. The clinical phenotype was variable in patients with and without pathogenic variants; no significant genotype-phenotype correlation was observed.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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