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IHH, Polyclonal Antibody

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產(chǎn)品名稱: IHH, Polyclonal Antibody
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IHH, Polyclonal Antibody


IHH, Polyclonal Antibody  的詳細(xì)介紹
Product Name

IHH, Polyclonal Antibody

Full Product Name

IHH Polyclonal Antibody

Product Synonym Names
BDA1; HHG-2; HHG2; IHH; IHH; Indian Hedgehog; Indian hedgehog homolog; Indian hedgehog protein; Indian hedgehog protein C-product; Indian hedgehog protein N-product
Product Gene Name

anti-IHH antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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3D Structure
ModBase 3D Structure for Q14623
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Concentration
0.8 mg/mL (lot specific)
Immunogen
Recombinant Human Indian hedgehog protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-IHH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-IHH antibody
This gene encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.
Product Categories/Family for anti-IHH antibody
Cancer; Stem Cells
Applications Tested/Suitable for anti-IHH antibody
Immunohistochemistry (IHC)
Application Notes for anti-IHH antibody
IHC: 1:100-1:400

Immunohistochemistry (IHC) of anti-IHH antibody
Immunohistochemistry of paraffin-embedded Human stomach using IHH Polyclonal Antibody at dilution of 1:100(100×)
anti-IHH antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-IHH antibody
Immunohistochemistry of paraffin-embedded Human stomach using IHH Polyclonal Antibody at dilution of 1:100(400×)
anti-IHH antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-IHH antibody
Immunohistochemistry of paraffin-embedded Human kidney using IHH Polyclonal Antibody at dilution of 1:100(100×)
anti-IHH antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-IHH antibody
Immunohistochemistry of paraffin-embedded Human kidney using IHH Polyclonal Antibody at dilution of 1:100(400×)
anti-IHH antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for IHH. It may not necessarily be applicable to this product.
NCBI GI #
119392086
NCBI GeneID
3549
NCBI Accession #
NP_002172.2 [Other Products]
NCBI GenBank Nucleotide #
NM_002181.4 [Other Products]
UniProt Primary Accession #
Q14623 [Other Products]
UniProt Secondary Accession #
O43322; Q8N4B9; B9EGM5[Other Products]
UniProt Related Accession #
Q14623[Other Products]
Molecular Weight
45,251 Da
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NCBI Official Full Name
indian hedgehog protein preproprotein
NCBI Official Synonym Full Names
Indian hedgehog signaling molecule
NCBI Official Symbol
IHH??[Similar Products]
NCBI Official Synonym Symbols
BDA1; HHG2
??[Similar Products]
NCBI Protein Information
indian hedgehog protein
UniProt Protein Name
Indian hedgehog protein
UniProt Synonym Protein Names
HHG-2
Protein Family
Indian hedgehog protein
UniProt Gene Name
IHH??[Similar Products]
UniProt Synonym Gene Names
IHH??[Similar Products]
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NCBI Summary for IHH
This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Nov 2015]
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UniProt Comments for IHH
Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) ().
Research Articles on IHH
1. TL1A modulated Rheumatoid arthritis-fibroblast-like synoviocytes migration and Indian hedgehog signaling pathway using TNFR2.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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