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ATP Binding Cassette Transporter C10, Polyclonal Antibody

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產(chǎn)品名稱: ATP Binding Cassette Transporter C10, Polyclonal Antibody
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ATP Binding Cassette Transporter C10, Polyclonal Antibody


ATP Binding Cassette Transporter C10, Polyclonal Antibody  的詳細(xì)介紹
Product Name

ATP Binding Cassette Transporter C10 (ABCC10), Polyclonal Antibody

Full Product Name

Polyclonal Antibody to ATP Binding Cassette Transporter C10 (ABCC10)

Product Gene Name

anti-ABCC10 antibody

[Similar Products]
Matching Pairs
Unconjugated Antibody: ATP Binding Cassette Transporter C10 (MBS2027446)
Immunogen: ATP Binding Cassette Transporter C10 (MBS2030449)
Matching Pairs
Unconjugated Antibody: ATP Binding Cassette Transporter C10 (MBS2027446)
APC-CY7 Conjugated Antibody: ATP Binding Cassette Transporter C10 (ABCC10) (MBS2084851)
Matching Pairs
Unconjugated Antibody: ATP Binding Cassette Transporter C10 (MBS2027446)
PE Conjugated Antibody: ATP Binding Cassette Transporter C10 (ABCC10) (MBS2084852)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
AY032599 mRNA
3D Structure
ModBase 3D Structure for Q5T3U5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Specificity
The antibody is a rabbit polyclonal antibody raised against ABCC10. It has beenselected for its ability to recognize ABCC10 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
200ug/ml (lot specific)
Fragment
ABCC10 (Val1246~Pro1492)
Organism Species
Homo sapiens (Human)
Conjugate
No Conjugate
Immunogen
Recombinant ABCC10 (Val1246~Pro1492) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2084853
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Other Notes
Small volumes of anti-ABCC10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Applications Tested/Suitable for anti-ABCC10 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-ABCC10 antibody
Western blotting: 0.2-2ug/mL;1:250-2500
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.

Western Blot (WB) of anti-ABCC10 antibody
Western Blot: Sample: Recombinant protein.
anti-ABCC10 antibody Western Blot (WB) (WB) image
Immunohistochemistry (IHC) of anti-ABCC10 antibody
DAB staining on IHC-P; Samples: Human Kidney Tissue)
anti-ABCC10 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ABCC10. It may not necessarily be applicable to this product.
NCBI GI #
312176403
NCBI GeneID
89845
NCBI Accession #
NP_001185863.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001198934.1 [Other Products]
UniProt Primary Accession #
Q5T3U5 [Other Products]
UniProt Secondary Accession #
Q8NHX7; Q9H7N2; Q9NXY3; Q9UF48[Other Products]
UniProt Related Accession #
Q5T3U5[Other Products]
Molecular Weight
158,781 Da
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NCBI Official Full Name
multidrug resistance-associated protein 7 isoform MRP7
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 10
NCBI Official Symbol
ABCC10??[Similar Products]
NCBI Official Synonym Symbols
MRP7; SIMRP7; EST182763
??[Similar Products]
NCBI Protein Information
multidrug resistance-associated protein 7
UniProt Protein Name
Multidrug resistance-associated protein 7
UniProt Synonym Protein Names
ATP-binding cassette sub-family C member 10
Protein Family
ABC transporter C family
UniProt Gene Name
ABCC10??[Similar Products]
UniProt Synonym Gene Names
MRP7; SIMRP7??[Similar Products]
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NCBI Summary for ABCC10
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2010]
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UniProt Comments for ABCC10
ABCC10: ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ABC family

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: integral component of plasma membrane; lysosomal membrane; plasma membrane

Molecular Function: anion transmembrane-transporting ATPase activity; ATP binding; ATPase activity, coupled to transmembrane movement of substances

Biological Process: transmembrane transport
Research Articles on ABCC10
1. It is thus inferred, that ABCC10 expression in CWR22Rv1 cells is not S phase-specific but is primarily associated with cell proliferation.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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