Amelogenin X isoform isoform 1; Amelogenin; X isoform isoform 1; Amelogenin; X-linked; AI1E; AIH1; ALGN; AMG; AMGL; AMGX

For Research Use Only. Not for use in diagnostic procedures.

E Coli

> 90% by SDS-PAGE

Liquid. In 20mM Tris-HCl Buffer (pH 8.5) containing 0.2M NaCl, 30% glycerol, 1mM DTT

0.25 mg/ml (determined by Bradford assay) (lot specific)

Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

Small volumes of AMELX recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

AMELX is a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in AMELX cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms. Recombinant human AMELX protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.

Signal Transduction

SDS-PAGE

22 kDa (198aa), confirmed by MALDI-TOF

amelogenin, X-linked

amelogenin, X isoform

Amelogenin, X isoform

AMG; AMGX??[Similar Products]

This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.

Patir A, Seymen F, et al. (2008). Caries Res. 42 (5):394-400.; Zhu L, Tanimoto K, et al. (2009). Cells Tissues Organs. 189 (1-4):203-6.;

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