Product Name
Angiogenin-4 (Ang4), Recombinant Protein
Popular Item
Full Product Name
Recombinant Mouse Angiogenin-4 (Ang4)
Product Gene Name
Ang4 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
25-144aa; Full Length of Mature Protein
Sequence
QNERYEKFLR QHYDAKPNGR DDRYCESMMK ERKLTSPCKD VNTFIHGTKK NIRAICGKKG SPYGENFRIS NSPFQITTCT HSGASPRPPC GYRAFKDFRY IVIACEDGWP VHFDESFISP
3D Structure
ModBase 3D Structure for Q3TMQ6
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 85% as determined by SDS-PAGE. (lot specific)
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Organism
Mus musculus (Mouse)
Tag Information
N-terminal 6xHis-SUMO-tagged and C-terminal Myc-tagged
Storage Buffer
Tris-based buffer, 50% glycerol
Production Note
Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C.
The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Ang4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Ang4 recombinant protein
Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro).
Product Categories/Family for Ang4 recombinant protein
Cardiovascular
SDS-Page of Ang4 recombinant protein
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Ang4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_808212.2
[Other Products]
NCBI GenBank Nucleotide #
NM_177544.4
[Other Products]
UniProt Primary Accession #
Q3TMQ6
[Other Products]
UniProt Secondary Accession #
Q3UWE7; Q80XS4; Q80Z85[Other Products]
UniProt Related Accession #
Q3TMQ6[Other Products]
Molecular Weight
31.4 kDa
NCBI Official Full Name
angiogenin-4
NCBI Official Synonym Full Names
angiogenin, ribonuclease A family, member 4
NCBI Official Symbol
Ang4??[Similar Products]
NCBI Official Synonym Symbols
Raa4; Rnase5d
??[Similar Products]
NCBI Protein Information
angiogenin-4
UniProt Protein Name
Angiogenin-4
Protein Family
Angiogenin
UniProt Gene Name
Ang4??[Similar Products]
UniProt Comments for Ang4
Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro).
Product References and Citations for Ang4 recombinant protein
"Identification of a purine-rich intronic enhancer element in the mouse eosinophil-associated ribonuclease 2 (mEar 2) gene." Dyer K.D., Nitto T., Moreau J.M., McDevitt A.L., Rosenberg H.F.Mamm. Genome 15:126-134 (2004)
Research Articles on Ang4
1. Intestinal intraepithelial lymphocyte-enterocyte crosstalk regulates production of bactericidal angiogenin 4 by Paneth cells upon microbial challenge.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
