Product Name
Angiogenin-4 (Ang4), Recombinant Protein
Full Product Name
Recombinant Mouse Angiogenin-4 (Ang4)
Product Gene Name
Ang4 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
Full Length, 25-144aa
3D Structure
ModBase 3D Structure for Q3TMQ6
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
Tris-based buffer, 50% glycerol
Tag Info
N-terminal 6xHis-SUMO-tagged
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
Other Notes
Small volumes of Ang4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Ang4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_808212.2
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NCBI GenBank Nucleotide #
NM_177544.4
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UniProt Primary Accession #
Q3TMQ6
[Other Products]
UniProt Secondary Accession #
Q3UWE7; Q80XS4; Q80Z85[Other Products]
UniProt Related Accession #
Q3TMQ6[Other Products]
Molecular Weight
29.92 kDa
NCBI Official Full Name
angiogenin-4
NCBI Official Synonym Full Names
angiogenin, ribonuclease A family, member 4
NCBI Official Symbol
Ang4??[Similar Products]
NCBI Official Synonym Symbols
Raa4; Rnase5d
??[Similar Products]
NCBI Protein Information
angiogenin-4
UniProt Protein Name
Angiogenin-4
Protein Family
Angiogenin
UniProt Gene Name
Ang4??[Similar Products]
UniProt Comments for Ang4
ANG4: Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). Belongs to the pancreatic ribonuclease family.
Protein type: EC 3.1.27.-
Chromosomal Location of Human Ortholog: 14|14 C1
Cellular Component: extracellular space; secretory granule
Molecular Function: endonuclease activity; ribonuclease activity
Biological Process: angiogenesis; antibacterial humoral response; defense response to bacterium; positive regulation of cell proliferation; RNA catabolic process
Research Articles on Ang4
1. Intestinal intraepithelial lymphocyte-enterocyte crosstalk regulates production of bactericidal angiogenin 4 by Paneth cells upon microbial challenge.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
