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glutamate receptor, ionotropic, N-methyl-D-aspartate 3A, ELISA Kit

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產(chǎn)品名稱: glutamate receptor, ionotropic, N-methyl-D-aspartate 3A, ELISA Kit
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glutamate receptor, ionotropic, N-methyl-D-aspartate 3A, ELISA Kit


glutamate receptor, ionotropic, N-methyl-D-aspartate 3A, ELISA Kit  的詳細(xì)介紹
Product Name

glutamate receptor, ionotropic, N-methyl-D-aspartate 3A (GRIN3A), ELISA Kit

Full Product Name

Human Glutamate [NMDA] receptor subunit 3A, GRIN3A ELISA Kit

Product Synonym Names
Human Glutamate [NMDA] receptor subunit 3A (GRIN3A) ELISA kit; FLJ45414; NMDAR-L; NR3A; ; glutamate receptor; ionotropic; N-methyl-D-aspartate 3A
Product Gene Name

GRIN3A elisa kit

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
Request Current Manual
OMIM
606650
3D Structure
ModBase 3D Structure for Q8TCU5
Species Reactivity
Human
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of GRIN3A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for GRIN3A purchase
MBS9337285 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the glutamate receptor, ionotropic, N-methyl-D-aspartate 3A (GRIN3A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GRIN3A. The ELISA analytical biochemical technique of the MBS9337285 kit is based on GRIN3A antibody-GRIN3A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GRIN3A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GRIN3A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for GRIN3A. It may not necessarily be applicable to this product.
NCBI GI #
223278356
NCBI GeneID
116443
NCBI Accession #
NP_597702.2 [Other Products]
NCBI GenBank Nucleotide #
NM_133445.2 [Other Products]
UniProt Primary Accession #
Q8TCU5 [Other Products]
UniProt Secondary Accession #
Q5VTR3; Q8TF29; Q8WXI6; B3DLF9[Other Products]
UniProt Related Accession #
Q8TCU5[Other Products]
Molecular Weight
125,465 Da
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NCBI Official Full Name
glutamate receptor ionotropic, NMDA 3A
NCBI Official Synonym Full Names
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
NCBI Official Symbol
GRIN3A??[Similar Products]
NCBI Official Synonym Symbols
NR3A; GluN3A; NMDAR-L
??[Similar Products]
NCBI Protein Information
glutamate receptor ionotropic, NMDA 3A; NMDAR3A; glutamate [NMDA] receptor subunit 3A; N-methyl-D-aspartate receptor subtype 3A
UniProt Protein Name
Glutamate receptor ionotropic, NMDA 3A
UniProt Synonym Protein Names
N-methyl-D-aspartate receptor subtype 3A; NMDAR3A; NR3A; NMDAR-L
Protein Family
Glutamate receptor ionotropic
UniProt Gene Name
GRIN3A??[Similar Products]
UniProt Synonym Gene Names
KIAA1973; GluN3A; NMDAR3A; NR3A??[Similar Products]
UniProt Entry Name
NMD3A_HUMAN
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NCBI Summary for GRIN3A
This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity. [provided by RefSeq, Jul 2008]
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UniProt Comments for GRIN3A
NMDAR3A: NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. May play a role in the development of dendritic spines. May play a role in PPP2CB-NMDAR mediated signaling mechanism. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3A/GRIN3A subfamily.

Protein type: Membrane protein, integral; Channel, ligand-gated; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 9q31.1

Cellular Component: postsynaptic membrane; neuron projection; cell soma; membrane; dendrite; postsynaptic density; integral to membrane; synapse; cell junction; N-methyl-D-aspartate selective glutamate receptor complex

Molecular Function: identical protein binding; neurotransmitter binding; protein binding; extracellular-glutamate-gated ion channel activity; protein phosphatase 2A binding; N-methyl-D-aspartate selective glutamate receptor activity; calcium channel activity; glycine binding

Biological Process: synaptic transmission, glutamatergic; response to ethanol; prepulse inhibition; ionotropic glutamate receptor signaling pathway; calcium ion transport; rhythmic process; dendrite development
Research Articles on GRIN3A
1. This review highlights GluN3A properties and addresses its role in neurophysiology and associated pathologies--{REVIEW}
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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