Product Name
PAH, cDNA Clone
Popular Item
Full Product Name
PAH cDNA Clone
Product Gene Name
PAH cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgtccactg cggtcctgga aaacccaggc ttgggcagga aactctctga ctttggacag gaaacaagct atattgaaga caactgcaat caaaatggtg ccatatcgct gatcttctca ctcaaagaag aagttggtgc attggccaaa gtattgcgct tatttgagga gaatgatgta aacctgaccc acattgaatc tagaccttct cgtttaaaga aagatgagta tgaatttttc acccatttgg ataaacgtag cctgcctgct ctgacaaaca tcatcaagat cttgaggcat gacattggtg ccactgtcca tgagctttca cgagataaga agaaagacac agtgccctgg ttcccaagaa ccattcaaga gctggacaga tttgccaatc agattctcag ctatggagcg gaactggatg ctgaccaccc tggttttaaa gatcctgtgt accgtgcaag acggaagcag tttgctgaca ttgcctacaa ctaccgccat gggcagccca tccctcgagt ggaatacatg gaggaaggaa agaaaacatg gggcacagtg ttcaagactc tgaagtcctt gtataaaacc catgcttgct atgagtacaa tcacattttt ccacttcttg aaaagtactg tggcttccat gaagataaca ttccccagct ggaagacgtt tctcagttcc tgcagacttg cactggtttc cgcctccgac ctgtggctgg cctgctttcc tctcgggatt tcttgggtgg cctggccttc cgagtcttcc actgcacaca gtacatcaga catggatcca agcccatgta tacccccgaa cctgacatct gccatgagct gttgggacat gtgcccttgt tttcagatcg cagctttgcc cagttttccc aggaaattgg ccttgcctct ctgggtgcac ctgatgaata cattgaaaag ctcgccacaa tttactggtt tactgtggag tttgggctct gcaaacaagg agactccata aaggcatatg gtgctgggct cctgtcatcc tttggtgaat tacagtactg cttatcagag aagccaaagc ttctccccct ggagctggag aagacagcca tccaaaatta cactgtcacg gagttccagc ccctctatta cgtggcagag agttttaatg atgccaagga gaaagtaagg aactttgctg ccacaatacc tcggcccttc tcagttcgct acgacccata cacccaaagg attgaggtct tggacaatac ccagcagctt aagattttgg ctgattccat taacagtgaa attggaatcc tttgcagtgc cctccagaaa ataaagtaa
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of PAH cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for PAH. It may not necessarily be applicable to this product.
NCBI Accession #
BC026251
[Other Products]
UniProt Secondary Accession #
Q16717; Q8TC14[Other Products]
UniProt Related Accession #
P00439[Other Products]
Molecular Weight
51,862 Da
NCBI Official Full Name
Homo sapiens phenylalanine hydroxylase, mRNA
NCBI Official Synonym Full Names
phenylalanine hydroxylase
NCBI Official Symbol
PAH??[Similar Products]
NCBI Official Synonym Symbols
PH; PKU; PKU1
??[Similar Products]
NCBI Protein Information
phenylalanine-4-hydroxylase
UniProt Protein Name
Phenylalanine-4-hydroxylase
UniProt Synonym Protein Names
Phe-4-monooxygenase
Protein Family
Phenylalanine-4-hydroxylase
UniProt Gene Name
PAH??[Similar Products]
UniProt Synonym Gene Names
PAH??[Similar Products]
UniProt Entry Name
PH4H_HUMAN
NCBI Summary for PAH
PAH encodes the enzyme phenylalanine hydroxylase that is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. [provided by RefSeq, Jul 2008]
UniProt Comments for PAH
PAH: phenylalanine hydroxylase that is the rate-limiting step in phenylalanine catabolism. Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.
Protein type: Oxidoreductase; Amino Acid Metabolism - phenylalanine, tyrosine and tryptophan biosynthesis; EC 1.14.16.1
Chromosomal Location of Human Ortholog: 12q22-q24.2
Cellular Component: cytosol
Molecular Function: phenylalanine 4-monooxygenase activity
Biological Process: amino acid biosynthetic process; L-phenylalanine catabolic process
Disease: Phenylketonuria
Research Articles on PAH
1. The mutation spectrum of PAH gene in Henan seems to differ from that of other regions. Independent assortment of mutant alleles may result in a complex genotype-phenotype correlation.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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