Product Name
Mesothelin (MSLN), ELISA Kit
Full Product Name
Human Mesothelin ELISA Kit
Product Synonym Names
Mesothelin; CAK1 antigen; Pre-pro-megakaryocyte-potentiating factor; MSLN; MPF
Product Gene Name
MSLN elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q13421
Samples
Serum, plasma, tissue homogenates and other
biological fluids.
Detection Range
0.78-50 ng/mL
Sensitivity
Less than 0.098ng/mL
Detection Wavelength
450 nm
Preparation and Storage
Store at 4 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of MSLN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for MSLN purchase
MBS9428276 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Mesothelin (MSLN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MSLN. The ELISA analytical biochemical technique of the MBS9428276 kit is based on MSLN antibody-MSLN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MSLN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MSLN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for MSLN. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001170826.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001177355.2
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UniProt Primary Accession #
Q13421
[Other Products]
UniProt Secondary Accession #
Q14859; Q4VQD5; Q96GR6; Q96KJ5; Q9BR17; Q9BTR2; Q9UCB2; Q9UK57; D3DU65[Other Products]
UniProt Related Accession #
Q13421[Other Products]
Molecular Weight
67,940 Da
NCBI Official Full Name
mesothelin isoform 1 preproprotein
NCBI Official Synonym Full Names
mesothelin
NCBI Official Symbol
MSLN??[Similar Products]
NCBI Official Synonym Symbols
MPF; SMRP
??[Similar Products]
NCBI Protein Information
mesothelin
UniProt Protein Name
Mesothelin
UniProt Synonym Protein Names
CAK1 antigen; Pre-pro-megakaryocyte-potentiating factor
Protein Family
Mesothelin
UniProt Gene Name
MSLN??[Similar Products]
UniProt Synonym Gene Names
MPF; MPF??[Similar Products]
NCBI Summary for MSLN
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
UniProt Comments for MSLN
MSLN: Membrane-anchored forms may play a role in cellular adhesion. Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer. Belongs to the mesothelin family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: cell surface; endoplasmic reticulum lumen; extracellular region; plasma membrane
Molecular Function: protein binding
Biological Process: C-terminal protein lipidation; cell-matrix adhesion; cellular protein metabolic process; post-translational protein modification
Research Articles on MSLN
1. MSLN expression increases cell migration and invasion in vitro.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
