Product Name
Mesothelin (MSLN), Recombinant Protein
Full Product Name
Recombinant mouse Mesothelin
Product Synonym Names
Pre-pro-megakaryocyte-potentiating factor
Product Gene Name
MSLN recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
Mesothelin, cleaved form, 298-600aa
3D Structure
ModBase 3D Structure for Q61468
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
20mM Tris-HCl based buffer, pH8.0
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Other Notes
Small volumes of MSLN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
MSLN recombinant protein
Mbrane-anchored forms may play a role in cellular adhesion.
NCBI/Uniprot data below describe general gene information for MSLN. It may not necessarily be applicable to this product.
NCBI Accession #
NP_061345.1
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NCBI GenBank Nucleotide #
NM_018857.1
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UniProt Primary Accession #
Q61468
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UniProt Related Accession #
Q61468[Other Products]
NCBI Official Full Name
mesothelin
NCBI Official Synonym Full Names
mesothelin
NCBI Official Symbol
Msln??[Similar Products]
NCBI Official Synonym Symbols
MPF
??[Similar Products]
NCBI Protein Information
mesothelin
UniProt Protein Name
Mesothelin
UniProt Synonym Protein Names
Pre-pro-megakaryocyte-potentiating factor
Protein Family
Mesothelin
UniProt Gene Name
Msln??[Similar Products]
UniProt Synonym Gene Names
Mes; Mpf; MPF??[Similar Products]
UniProt Comments for MSLN
MSLN: Membrane-anchored forms may play a role in cellular adhesion. Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer. Belongs to the mesothelin family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 17|17 A3.3
Cellular Component: cell surface; extracellular space
Molecular Function: protein binding
Biological Process: cell-matrix adhesion
Research Articles on MSLN
1. Results show that mouse mesothelin is similar to human mesothelin. Its stable overexpression in a pancreatic cancer cell line did not increase cell proliferation, suggesting that mesothelin is not necessarily a tumor progression factor.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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