Product Name
ASTN2, Blocking Peptide
Full Product Name
ASTN2 Blocking Peptide(N-term)
Product Synonym Names
Astrotactin-2; ASTN2; KIAA0634
Product Gene Name
ASTN2 blocking peptide
[Similar Products]
Product Synonym Gene Name
KIAA0634[Similar Products]
ASTN2 peptide (MBS9228579) is used for blocking the activity of ASTN2 antibody (MBS9210824)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O75129
Specificity
The synthetic peptide sequence is selected from aa 235-248 of HUMAN ASTN2
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Membrane; Multi-pass membrane protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of ASTN2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ASTN2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001171664.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001184735.1
[Other Products]
UniProt Primary Accession #
O75129
[Other Products]
UniProt Secondary Accession #
Q52LQ2; Q5JVX8; Q5JVX9; Q5JVY1; Q5VXG8; Q5VZX6; Q8N6P8; Q8WV47; Q96FL4; A2A2T7; A2A2T9[Other Products]
UniProt Related Accession #
O75129[Other Products]
Molecular Weight
44,561 Da
NCBI Official Full Name
astrotactin-2 isoform f
NCBI Official Synonym Full Names
astrotactin 2
NCBI Official Symbol
ASTN2??[Similar Products]
NCBI Official Synonym Symbols
bA67K19.1
??[Similar Products]
NCBI Protein Information
astrotactin-2
UniProt Protein Name
Astrotactin-2
Protein Family
Astrotactin
UniProt Gene Name
ASTN2??[Similar Products]
UniProt Synonym Gene Names
KIAA0634??[Similar Products]
UniProt Entry Name
ASTN2_HUMAN
NCBI Summary for ASTN2
This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus. [provided by RefSeq, May 2010]
UniProt Comments for ASTN2
ASTN2: a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus. [provided by RefSeq, May 2010]
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 9q33.1
Research Articles on ASTN2
1. Study found a significant association of ASTN2 genetic variants with age at onset in Alzheimer's disease in two independent samples together with in silico analysis that demonstrated potential role of ASTN2 in the pathogenesis of the disease
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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