Product Name
ASTN2, Blocking Peptide
Full Product Name
ASTN2 Peptide - N-terminal region
Product Gene Name
ASTN2 blocking peptide
[Similar Products]
Product Synonym Gene Name
KIAA0634; bA67K19.1[Similar Products]
ASTN2 peptide (MBS3233356) is used for blocking the activity of ASTN2 antibody (MBS3208394)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O75129
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of ASTN2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ASTN2 blocking peptide
This is a synthetic peptide designed for use in combination with anti-ASTN2 antibody made
Target Description: ASTN2 may play an important role in neuronal functioning.
Product Categories/Family for ASTN2 blocking peptide
Peptide
Applications Tested/Suitable for ASTN2 blocking peptide
Western Blot (WB), Immunocytochemistry (ICC)
NCBI/Uniprot data below describe general gene information for ASTN2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_054729
[Other Products]
NCBI GenBank Nucleotide #
NM_014010
[Other Products]
UniProt Primary Accession #
O75129
[Other Products]
UniProt Related Accession #
O75129[Other Products]
NCBI Official Full Name
astrotactin-2 isoform a
NCBI Official Synonym Full Names
astrotactin 2
NCBI Official Symbol
ASTN2??[Similar Products]
NCBI Official Synonym Symbols
bA67K19.1
??[Similar Products]
NCBI Protein Information
astrotactin-2
UniProt Protein Name
Astrotactin-2
Protein Family
Astrotactin
UniProt Gene Name
ASTN2??[Similar Products]
UniProt Synonym Gene Names
KIAA0634??[Similar Products]
NCBI Summary for ASTN2
This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus. [provided by RefSeq, May 2010]
UniProt Comments for ASTN2
Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref. 6).
Research Articles on ASTN2
1. ASTN2 localizes primarily to endocytic and autophagocytic vesicles in the cell soma and in subsets of dendritic spines
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
