Full Product Name
ASTN2 Rabbit Polyclonal
Product Gene Name
anti-ASTN2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-ASTN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ASTN2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for ASTN2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_054729.3
[Other Products]
NCBI GenBank Nucleotide #
NM_014010.4
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UniProt Secondary Accession #
Q52LQ2; Q5JVX8; Q5JVX9; Q5JVY1; Q5VXG8; Q5VZX6; Q8N6P8; Q8WV47; Q96FL4; A2A2T7; A2A2T9[Other Products]
UniProt Related Accession #
O75129[Other Products]
Molecular Weight
44,561 Da
NCBI Official Full Name
astrotactin-2 isoform a
NCBI Official Synonym Full Names
astrotactin 2
NCBI Official Symbol
ASTN2??[Similar Products]
NCBI Official Synonym Symbols
bA67K19.1
??[Similar Products]
NCBI Protein Information
astrotactin-2
UniProt Protein Name
Astrotactin-2
Protein Family
Astrotactin
UniProt Gene Name
ASTN2??[Similar Products]
UniProt Synonym Gene Names
KIAA0634??[Similar Products]
UniProt Entry Name
ASTN2_HUMAN
NCBI Summary for ASTN2
This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus. [provided by RefSeq, May 2010]
UniProt Comments for ASTN2
ASTN2: a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus. [provided by RefSeq, May 2010]
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 9q33.1
Cellular Component: endosome; integral to membrane
Research Articles on ASTN2
1. Study found a significant association of ASTN2 genetic variants with age at onset in Alzheimer's disease in two independent samples together with in silico analysis that demonstrated potential role of ASTN2 in the pathogenesis of the disease
Precautions
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Disclaimer
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