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ATP12A, cDNA Clone

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產品名稱: ATP12A, cDNA Clone
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ATP12A, cDNA Clone


ATP12A, cDNA Clone  的詳細介紹
Product Name

ATP12A, cDNA Clone

Full Product Name

ATP12A cDNA Clone

Product Gene Name

ATP12A cdna clone

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence
atgcaccaga aaaccccaga aatttactcc gtggagctca gcggaactaa ggacatcgtg aaaacagaca agggggatgg caaggagaag tataggggtc tgaagaacaa ctgcctggaa ctcaaaaaga aaaatcacaa agaggagttt cagaaagaac tccatctgga tgaccacaaa ctcagcaata gggaattgga agagaaatat ggcacagaca tcattatggg tctctccagc accagagctg ccgagctcct ggcccgggat gggcccaact ccctcacccc tcccaagcag acgcctgaga tcgtcaagtt cctcaagcag atggtggggg ggttctctat cctcctgtgg gtgggcgcct ttctctgttg gattgcatat gggattcagt actccagcga caagtctgca tccctgaaca acgtgtactt gggctgtgtg cttggtctgg tggtcatttt aacggggatc tttgcttatt accaagaggc aaaaagcacc aacatcatgt ccagcttcaa taagatgatc cctcagcaag ctctcgtcat ccgagattcc gagaagaaga ccatcccttc agagcagctg gtggtggggg acattgtgga ggtcaaagga ggagaccaga tccctgcaga catcagggtg ctgtcttctc aggggtgtcg ggtggataac tcatctctca cgggggagtc tgagccccag ccccgctcct ctgagtttac ccatgaaaac cccctggaaa caaagaacat ctgcttctat tccacaacgt gtctggaagc atctacttcc cctgtaggca ctgtcaccgg catggttatc aacacgggtg accgcaccat cattggccat attgcctcat tggcctcagg agttggaaat gagaagacgc ccattgccat tgagatcgag cactttgttc acattgtggc aggagtggct gtctccatcg gcatcctttt cttcatcatc gctgtgtccc tgaagtatca agtcctggac tccatcatct tcctcattgg catcattgtg gccaatgtgc ccgagggcct cctggccact gtcactgtga ccctgtcgct gacagcaaaa cggatggcca agaagaactg cctggtgaag aacctggagg ctgtggagac cctcggctcc acctccatca tctgctcgga caagactggg acactgaccc agaacaggat gacagtggcc catctgtggt tcgacaatca gatctttgtg gctgacacca gtgaggacca ttcaaaccaa gtctttgacc aaagctctag gacttgggcc tccttatcca agataataac attgtgtaac cgagcagagt tcaagccagg acaggaaaat gtccccatca tgaagaaagc tgtgattgga gatgcctcag aaactgctct tttaaaattc tcagaggtca ttttgggtga tgtgatggaa attagaaaaa gaaaccgcaa agtagctgaa atccctttta actctactaa taaatttcag ctctccatcc acgagatgga tgacccccac ggcaagcgct tcctcatggt gatgaagggg gcccctgagc gcattctaga gaaatgcagc accatcatga tcaacggcga ggagcaccca ctggacaaga gcactgccaa gaccttccac acagcctaca tggagctggg cgggttgggc gagcgtgtgc tgggtttctg tcatctctac ctgccagcag acgagtttcc agaaacctac tcatttgaca tagacgctat gaactttccg acctccaacc tctgttttgt gggactcttg tcaatgatcg atccccctcg gtccaccgtg ccagatgcag tcaccaaatg ccggagtgca gggatcaagg ttattatggt tactggtgat catcccatca cagccaaagc tattgccaag agtgtgggga tcatttcagc caacagtgaa acagtggaag acattgcaca tcgcctcaac attgctgtgg agcaagttaa caaacgggat gccaaggccg ctgtggtgac tggcatggag ctgaaggaca tgagctcaga acagctggat gagatcttag ccaactacca ggagattgtc tttgcccgga catcccccca gcagaagctg atcattgtgg agggctgtca gaggcaggat gctgttgttg ctgtgaccgg ggatggagtt aatgactctc cggctctaaa gaaggcagac attgggattg ccatggggat agcaggttct gatgcagcca aaaatgcagc cgacatggtc ttgctggacg acaacttcgc atccatcgtc acaggggtgg aggaaggtcg cctgatcttt gacaacctca agaagactat tgcttattcc ctgaccaaga acattgccga gctgtgcccc tttctgatct acatcattgt cgggctcccc ctgcccattg gcaccatcac cattctgttc attgacttgg ggacagacat tatcccctcc attgccttgg cgtacgagaa agctgaaagt gacatcatga acaggaagcc tcgccacaag aataaggaca ggctggtgaa ccagccgctc gctgtgtact catacctgca cattggcctc atgcaagccc tgggagcttt ccttgtgtat ttcaccgtct atgcacaaga gggctttctg ccccgcactc tcattaacct gcgggtagaa tgggagaagg actacgtgaa tgacttgaaa gacagctatg ggcaggaatg gacaaggtac cagagggaat acctagaatg gacgggctac acggctttct ttgttggcat cctagtccag caaatagcag atctgatcat caggaaaacc cggaggaatt ccatcttcca gcagggtctc ttcagaaata aagtcatctg ggtggggatc acctcacaga tcatcattgg tctgatcctc tcctatggcc tcggaagtgt cacagccttg agtttcacca tgcttagggc tcagtactgg tttgtggctg tgccgcacgc catcctgatc tgggtgtatg atgaggtgcg gaagctcttc atcaggctct accctggaag ctggtgggat aagaacatgt attattaa
OMIM
182360
Vector
pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ATP12A cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ATP12A. It may not necessarily be applicable to this product.
NCBI GI #
21618763
NCBI GeneID
479
NCBI Accession #
BC031609 [Other Products]
UniProt Secondary Accession #
Q13816; Q13817; Q16734; Q5W035; Q8N5U2[Other Products]
UniProt Related Accession #
P54707[Other Products]
Molecular Weight
116,053 Da
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NCBI Official Full Name
Homo sapiens ATPase, H+/K+ transporting, nongastric, alpha polypeptide, mRNA
NCBI Official Synonym Full Names
ATPase H+/K+ transporting non-gastric alpha2 subunit
NCBI Official Symbol
ATP12A??[Similar Products]
NCBI Official Synonym Symbols
HK; #945; ATP1AL1
??[Similar Products]
NCBI Protein Information
potassium-transporting ATPase alpha chain 2
UniProt Protein Name
Potassium-transporting ATPase alpha chain 2
UniProt Synonym Protein Names
Non-gastric H(+)/K(+) ATPase subunit alpha; Proton pump
Protein Family
Potassium-transporting ATPase
UniProt Gene Name
ATP12A??[Similar Products]
UniProt Synonym Gene Names
ATP1AL1??[Similar Products]
UniProt Entry Name
AT12A_HUMAN
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NCBI Summary for ATP12A
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
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UniProt Comments for ATP12A
ATP12A: Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.6.3.10; Hydrolase; Transporter; Membrane protein, multi-pass; Membrane protein, integral; Energy Metabolism - oxidative phosphorylation; Transporter, ion channel

Chromosomal Location of Human Ortholog: 13q12.12|13q12.1-q12.3

Cellular Component: hydrogen:potassium-exchanging ATPase complex; intracellular membrane-bound organelle; plasma membrane

Molecular Function: hydrogen:potassium-exchanging ATPase activity; sodium:potassium-exchanging ATPase activity

Biological Process: ATP hydrolysis coupled proton transport; cellular potassium ion homeostasis; cellular sodium ion homeostasis; potassium ion import
Research Articles on ATP12A
1. expressing human ATP12A in cystic fibrosis mouse airways acidified airway surface liquid, impaired defenses, and increased airway bacteria.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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