DA7; Fetal myosin heavy chain; gtMHC F; MYH8; MYH8_HUMAN; MyHC peri; MyHC pn; MyHC-perinatal; Myosin heavy chain 8; Myosin heavy chain; Myosin heavy chain, skeletal muscle, perinatal; Myosin, heavy chain 8, skeletal muscle, perinatal; Myosin, heavy polypeptide 8, skeletal muscle, perinatal; Myosin-8; perinatal; skeletal muscle

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

MYH8 antibody detects endogenous levels of total MYH8

The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.

Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

1mg/ml (lot specific)

Store at -20 degree C. Stable for 12 months from date of receipt.

Manufactured in an ISO 9001:2015 Certified Laboratory.

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Small volumes of anti-MYH8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Function: Muscle contraction.
Subunit Structure: Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).
Similarity: The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.Limited proteolysis of myosin heavy chain produces 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). HMM can be further cleaved into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2). Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

Western Blot (WB), ELISA (EIA)

WB: 1:1000-3000

Western blot analysis of MYH8 using HepG2 whole cell lysates

Observed: 223 kDa
Predicted: 223 kDa

myosin heavy chain 8

myosin-8

Myosin-8

MyHC-perinatal??[Similar Products]

Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome. [provided by RefSeq, Sep 2009]

Muscle contraction.

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