Product Name
Ferritin light chain (FTL), Protein
Full Product Name
Ferritin light chain
Product Gene Name
FTL protein
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Matching Pairs
Antibody: FTL (MBS2898835)
Antigen: Ferritin light chain (MBS2889395)
Matching Pairs
Antibody: FTL (MBS2898836)
Antigen: Ferritin light chain (MBS2889395)
Matching Pairs
Antibody: FTL (MBS2898837)
Antigen: Ferritin light chain (MBS2889395)
Matching Pairs
Antibody: FTL (MBS2898838)
Antigen: Ferritin light chain (MBS2889395)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-175aa
3D Structure
ModBase 3D Structure for P02792
Purity/Purification
>95% by SDS-PAGE
Endotoxin Level
<0.10 EU per 1 mug of the protein by the LAL method
Storage Buffer
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
Preparation and Storage
Store at -20 degree C.
Avoid repeated freezing and thawing.
Other Notes
Small volumes of FTL protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for FTL protein
ELISA (EIA), Western Blot (WB), Affinity Purification (AP), Protein Array
NCBI/Uniprot data below describe general gene information for FTL. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000137.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000146.3
[Other Products]
UniProt Primary Accession #
P02792
[Other Products]
UniProt Secondary Accession #
Q6IBT7; Q7Z2W1; Q86WI9; Q8WU07; Q96AU9; Q96CU0; Q9BTZ8; B2R4B9[Other Products]
UniProt Related Accession #
P02792[Other Products]
Molecular Weight
20,020 Da
NCBI Official Full Name
ferritin light chain
NCBI Official Synonym Full Names
ferritin light chain
NCBI Official Symbol
FTL??[Similar Products]
NCBI Official Synonym Symbols
LFTD; NBIA3
??[Similar Products]
NCBI Protein Information
ferritin light chain
UniProt Protein Name
Ferritin light chain
UniProt Gene Name
FTL??[Similar Products]
UniProt Synonym Gene Names
Ferritin L subunit??[Similar Products]
NCBI Summary for FTL
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]
UniProt Comments for FTL
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney ().
Research Articles on FTL
1. Determining serum ferritin is a convenient and nonexpensive method to determine the outcome of the treatment of the cases with oral squamous cell carcinoma . Its potential as prognostic marker could not be overlooked
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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