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SLC22A11, cDNA Clone

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產(chǎn)品名稱: SLC22A11, cDNA Clone
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SLC22A11, cDNA Clone


SLC22A11, cDNA Clone  的詳細(xì)介紹
Product Name

SLC22A11, cDNA Clone

Full Product Name

SLC22A11 cDNA Clone

Product Gene Name

SLC22A11 cdna clone

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence
atggcgttct cgaagctctt ggagcaagcc ggaggcgtgg gcctcttcca gaccctgcag gtgctcacct tcatcctccc ctgcctcatg ataccttccc agatgctcct ggagaacttc tcagccgcca tcccaggcca ccgatgctgg acacacatgc tggacaatgg ctctgcggtt tccacaaaca tgacccccaa ggcccttctg accatctcca tcccgccagg ccccaaccag gggccccacc agtgccgccg cttccgccag ccacagtggc agctcttgga ccccaatgcc acggccacca gctggagcga agctgacacg gagccgtgtg tggacggctg ggtctatgac cgcagcgtct tcacctccac catcgtggcc aagtgggacc tggtgtgcag ctcccagggc ttgaagcccc taagccagtc catcttcatg tccgggatcc tggtgggctc ctttatctgg ggcctcctct cctaccggtt tgggaggaag ccgatgctga gctggtgctg cctgcagttg gccgtggcgg gcaccagcac catcttcgcc ccaacattcg tcatctactg cggcctgcgg ttcgtggccg cttttgggat ggccggcatc tttctgagtt cactgacact gatggtggag tggaccacga ccagcaggag ggcggtcacc atgacggtgg tgggatgtgc cttcagcgca ggccaggcgg cgctgggcgg cctggccttt gccctgcggg actggaggac tctccagctg gcagcatcag tgcccttctt tgccatctcc ctgatatcct ggtggctgcc agaatccgcc cggtggctga ttattaaggg caaaccagac caagcacttc aggagctcag aaaggtggcc aggataaatg gccacaagga ggccaagaac ctgaccatag aggtgctgat gtccagcgtg aaggaggagg tggcctctgc aaaggagccg cggtcggtgc tggacctgtt ctgcgtgccc gtgctccgct ggaggagctg cgccatgctg gtggtgaatt tctctctatt gatctcctac tatgggctgg tcttcgacct gcagagcctg ggccgtgaca tcttcctcct ccaggccctc ttcggggccg tggacttcct gggccgggcc accactgccc tcttgctcag tttccttggc cgccgcacca tccaggcggg ttcccaggcc atggccggcc tcgccattct agccaacatg ctggtgccgc aagatttgca gaccctgcgt gtggtctttg ctgtgctggg aaagggatgt tttgggataa gcctaacctg cctcaccatc tacaaggctg aactctttcc aacgccagtg cggatgacag cagatggcat tctgcataca gtgggccggc tgggggctat gatgggtccc ctgatcctga tgagccgcca agccctgccc ctgctgcctc ctctcctcta tggcgttatc tccattgctt ccagcctggt tgtgctgttc ttcctcccgg agacccaggg acttccgctc cctgacacta tccaggacct ggagagccag aaatcaacag cagcccaggg caaccggcaa gaggccgtca ctgtggaaag tacctcgctc tag
OMIM
607097
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SLC22A11 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for SLC22A11. It may not necessarily be applicable to this product.
NCBI GI #
21706713
NCBI GeneID
55867
NCBI Accession #
BC034384 [Other Products]
UniProt Secondary Accession #
Q53GR2; Q6ZP72; Q8NBU4; A8K426[Other Products]
UniProt Related Accession #
Q9NSA0[Other Products]
Molecular Weight
48,301 Da
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NCBI Official Full Name
Homo sapiens solute carrier family 22 (organic anion/urate transporter), member 11, mRNA
NCBI Official Synonym Full Names
solute carrier family 22 member 11
NCBI Official Symbol
SLC22A11??[Similar Products]
NCBI Official Synonym Symbols
OAT4; hOAT4
??[Similar Products]
NCBI Protein Information
solute carrier family 22 member 11
UniProt Protein Name
Solute carrier family 22 member 11
UniProt Synonym Protein Names
Organic anion transporter 4
Protein Family
Solute carrier family
UniProt Gene Name
SLC22A11??[Similar Products]
UniProt Synonym Gene Names
OAT4??[Similar Products]
UniProt Entry Name
S22AB_HUMAN
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NCBI Summary for SLC22A11
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
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UniProt Comments for SLC22A11
SLC22A11: Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Cell surface; Transporter, SLC family

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: apical plasma membrane; external side of plasma membrane; integral to plasma membrane; plasma membrane

Molecular Function: inorganic anion exchanger activity; organic anion transmembrane transporter activity; protein binding; sodium-independent organic anion transmembrane transporter activity

Biological Process: organic anion transport; sodium-independent organic anion transport; urate metabolic process
Research Articles on SLC22A11
1. modifies placental passage of perfluorinated alkyl acids, may decrease fetal exposure
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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