Product Name
SLC22A11, Polyclonal Antibody
Full Product Name
SLC22A11 Polyclonal Antibody
Product Synonym Names
OAT4; hOAT4
Product Gene Name
anti-SLC22A11 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purification
Immunogen
Recombinant protein of human SLC22A11
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162194 / sc-162195 / sc-162196 / sc-134005
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-SLC22A11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SLC22A11 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-SLC22A11 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:100
Western Blot (WB) of anti-SLC22A11 antibody
Western blot analysis of extracts of various cells, using SLC22A11 antibody.
Immunofluorescence (IF) of anti-SLC22A11 antibody
Immunofluorescence analysis of A549 cell using SLC22A11 antibody. Blue: DAPI for nuclear staining.
NCBI/Uniprot data below describe general gene information for SLC22A11. It may not necessarily be applicable to this product.
NCBI GenBank Nucleotide #
NM_001307985.1
[Other Products]
UniProt Secondary Accession #
Q53GR2; Q6ZP72; Q8NBU4; A8K426[Other Products]
UniProt Related Accession #
Q9NSA0[Other Products]
NCBI Official Full Name
solute carrier family 22 member 11 isoform 2
NCBI Official Synonym Full Names
solute carrier family 22 member 11
NCBI Official Symbol
SLC22A11??[Similar Products]
NCBI Official Synonym Symbols
OAT4; hOAT4
??[Similar Products]
NCBI Protein Information
solute carrier family 22 member 11
UniProt Protein Name
Solute carrier family 22 member 11
UniProt Synonym Protein Names
Organic anion transporter 4
Protein Family
Solute carrier family
UniProt Gene Name
SLC22A11??[Similar Products]
UniProt Synonym Gene Names
OAT4??[Similar Products]
UniProt Entry Name
S22AB_HUMAN
NCBI Summary for SLC22A11
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
UniProt Comments for SLC22A11
SLC22A11: Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell surface; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 11q13.1
Cellular Component: apical plasma membrane; external side of plasma membrane; integral to plasma membrane; plasma membrane
Molecular Function: inorganic anion exchanger activity; organic anion transmembrane transporter activity; protein binding; sodium-independent organic anion transmembrane transporter activity
Biological Process: organic anion transport; sodium-independent organic anion transport; urate metabolic process
Research Articles on SLC22A11
1. The first genome-wide association study for serum uric acid level in Indians revealed association of SLC2A9, SLC22A11 and ABCG2 gene variants at genome wide significance level in Type 2 diabetes patients.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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