Solute carrier family 22 member 11; Organic anion transporter 4; SLC22A11; OAT4

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

Antigen Affinity Purified

Liquid

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Small volumes of anti-SLC22A11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds.

ELISA (EIA), Immunohistochemistry (IHC)

Recommended dilution: IHC: 1:20-1:200

Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7045328 at dilution 1:100

Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7045328 at dilution 1:100

48,301 Da

solute carrier family 22 member 11

solute carrier family 22 member 11

Solute carrier family 22 member 11

OAT4??[Similar Products]

S22AB_HUMAN

The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

SLC22A11: Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Cell surface; Transporter

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: apical plasma membrane; external side of plasma membrane; integral to plasma membrane; plasma membrane

Molecular Function: inorganic anion exchanger activity; organic anion transmembrane transporter activity; protein binding; sodium-independent organic anion transmembrane transporter activity

Biological Process: organic anion transport; sodium-independent organic anion transport; urate metabolic process

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