Product Name
Gamma-sarcoglycan (Sgcg), Recombinant Protein
Full Product Name
Gamma-sarcoglycan
Product Gene Name
Sgcg recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-291aa; full length protein
Sequence
MVREQYTTVT EGTHIERPEN QHIYKIGIYG WRKRCLYLFV LLLLAILVVN LALTIWILKV MWFSPIGMGH LHVTADGLRL EGESEFLFPL YAKEIRSRVD SSLLLQSTQN VTVSARNSEG EVTGRVKVGA QMVEVQSQHF QINSEDGKPL FSAEEQDVVV GTGRLRVTGP EGALFEHSVE TPLVRADPFQ DLRLESPTRS LSMDAPRGVH VKANAGKLEA LSQMDIILQS SEGVLVLDAE TVGLTKLKQG TQGPAGSSNG FYEICACPDG KLYLSMAGEV TTCEEHSHVC L
3D Structure
ModBase 3D Structure for P82348
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Species
Mus musculus (Mouse)
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Sgcg recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Sgcg recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
Product Categories/Family for Sgcg recombinant protein
Transmembrane Protein
NCBI/Uniprot data below describe general gene information for Sgcg. It may not necessarily be applicable to this product.
NCBI Accession #
NP_036022.1
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NCBI GenBank Nucleotide #
NM_011892.3
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UniProt Primary Accession #
P82348
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UniProt Related Accession #
P82348[Other Products]
Molecular Weight
32,082 Da
NCBI Official Full Name
gamma-sarcoglycan
NCBI Official Synonym Full Names
sarcoglycan, gamma (dystrophin-associated glycoprotein)
NCBI Official Symbol
Sgcg??[Similar Products]
NCBI Official Synonym Symbols
35kDa; AI642964; gamma-SG; 5430420E18Rik
??[Similar Products]
NCBI Protein Information
gamma-sarcoglycan
UniProt Protein Name
Gamma-sarcoglycan
UniProt Synonym Protein Names
35 kDa dystrophin-associated glycoprotein; 35DAG
Protein Family
Gamma-sarcoglycan
UniProt Gene Name
Sgcg??[Similar Products]
UniProt Synonym Gene Names
Gamma-SG; 35DAG??[Similar Products]
UniProt Entry Name
SGCG_MOUSE
UniProt Comments for Sgcg
SGCG: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCG are the cause of limb-girdle muscular dystrophy type 2C (LGMD2C). LGMD2C is characterized by progressive muscle wasting from early childhood. Belongs to the sarcoglycan beta/delta/gamma/zeta family.
Protein type: Dystrophin complex; Membrane protein, integral
Cellular Component: dystroglycan complex; integral to plasma membrane; sarcoglycan complex; sarcolemma
Molecular Function: protein binding
Biological Process: cardiac muscle development; heart contraction; muscle cell development; muscle development
Disease: Muscular Dystrophy, Limb-girdle, Type 2c
Research Articles on Sgcg
1. for MD research. The Sgcg(-/-) mice have a more severe phenotype than the mdx mice. Muscle function was assessed by plethysmography and echocardiography. Histologically the Sgcg(-/-) mice displayed increased fibrosis and variable fiber size.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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