Product Name
GBA2, Blocking Peptide
Full Product Name
GBA2 Peptide - middle region
Product Gene Name
GBA2 blocking peptide
[Similar Products]
Product Synonym Gene Name
F630034E04[Similar Products]
GBA2 peptide (MBS3248358) is used for blocking the activity of GBA2 antibody (MBS3223754)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Synthetic peptide located within the following region: LMSGVVAPVK RRNVIPHDIG DPDDEPWLRV NAYLIHDTAD WKDLNLKFVL
3D Structure
ModBase 3D Structure for Q69ZF3
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of GBA2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
GBA2 blocking peptide
This is a synthetic peptide designed for use in combination with anti- GBA2 Antibody, made
Target Description: Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development (By similarity). Required for proper formation of motor neuron axons (By similarity).
Product Categories/Family for GBA2 blocking peptide
Peptide
NCBI/Uniprot data below describe general gene information for GBA2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_766280.2
[Other Products]
NCBI GenBank Nucleotide #
NM_172692.3
[Other Products]
UniProt Primary Accession #
Q69ZF3
[Other Products]
UniProt Related Accession #
Q69ZF3[Other Products]
NCBI Official Full Name
non-lysosomal glucosylceramidase
NCBI Official Synonym Full Names
glucosidase beta 2
NCBI Official Symbol
Gba2??[Similar Products]
NCBI Official Synonym Symbols
F630034E04
??[Similar Products]
NCBI Protein Information
non-lysosomal glucosylceramidase
UniProt Protein Name
Non-lysosomal glucosylceramidase
UniProt Synonym Protein Names
Beta-glucocerebrosidase 2; Beta-glucosidase 2; Glucosylceramidase 2
UniProt Gene Name
Gba2??[Similar Products]
UniProt Synonym Gene Names
Kiaa1605; NLGase; Beta-glucosidase 2??[Similar Products]
UniProt Entry Name
GBA2_MOUSE
Research Articles on GBA2
1. sphingosine, the cytotoxic metabolite accumulating in Gaucher cells through the action of GBA2, directly binds to GBA2 and inhibits its activity.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
