Product Name
sarcoglycan, gamma (SGCG), Polyclonal Antibody
Full Product Name
Rabbit anti-human sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) polyclonal Antibody
Product Synonym Names
sarcoglycan; gamma (35kDa dystrophin-associated glycoprotein); SGCG; A4; DAGA4; DMDA; DMDA1; LGMD2C; MAM; MGC130048; SCARMD2; SCG3; TYPE
Product Gene Name
anti-SGCG antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-14180 / sc-14181 / sc-28280 / sc-133984
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-SGCG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SGCG antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for SGCG. It may not necessarily be applicable to this product.
NCBI Accession #
AAI09322.1
[Other Products]
UniProt Secondary Accession #
Q32M32; Q5T9J6[Other Products]
UniProt Related Accession #
Q13326[Other Products]
Molecular Weight
32,379 Da[Similar Products]
NCBI Official Full Name
Sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
NCBI Official Synonym Full Names
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
NCBI Official Symbol
SGCG??[Similar Products]
NCBI Official Synonym Symbols
A4; MAM; DMDA; SCG3; TYPE; DAGA4; DMDA1; LGMD2C; SCARMD2
??[Similar Products]
NCBI Protein Information
gamma-sarcoglycan; 35DAG; gamma-SG; gamma sarcoglycan; 35kD dystrophin-associated glycoprotein; 35 kDa dystrophin-associated glycoprotein
UniProt Protein Name
Gamma-sarcoglycan
UniProt Synonym Protein Names
35 kDa dystrophin-associated glycoprotein; 35DAG
Protein Family
Gamma-sarcoglycan
UniProt Gene Name
SGCG??[Similar Products]
UniProt Synonym Gene Names
Gamma-SG; 35DAG??[Similar Products]
UniProt Entry Name
SGCG_HUMAN
NCBI Summary for SGCG
This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]
UniProt Comments for SGCG
SGCG: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCG are the cause of limb-girdle muscular dystrophy type 2C (LGMD2C). LGMD2C is characterized by progressive muscle wasting from early childhood. Belongs to the sarcoglycan beta/delta/gamma/zeta family.
Protein type: Membrane protein, integral; Dystrophin complex
Chromosomal Location of Human Ortholog: 13q12
Cellular Component: cytoskeleton; cytoplasm; plasma membrane; integral to membrane; sarcoglycan complex; sarcolemma
Molecular Function: protein binding
Biological Process: cardiac muscle development; muscle development; heart contraction; muscle cell development
Disease: Muscular Dystrophy, Limb-girdle, Type 2c
Research Articles on SGCG
1. Data suggest that an SNP in an intron of SGCG (rs9552911) is associated with type 2 diabetes [Genome-Wide Association Study in Sikh populations in India & Meta-Analysis]
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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