Full Product Name
Abca1 antibody - middle region
Product Gene Name
anti-ABCA1 antibody
[Similar Products]
Product Synonym Gene Name
Abc1[Similar Products]
Antibody/Peptide Pairs
Abca1 peptide (MBS3231946) is used for blocking the activity of Abca1 antibody (MBS3206980)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: NRRAFGDKQS CLHPFTEDDA VDPNDSDIDP ESRETDLLSG MDGKGSYQLK
3D Structure
ModBase 3D Structure for B1AWZ8
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 86%
Immunogen
The immunogen is a synthetic peptide corresponding to a region of Mouse
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ABCA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCA1 antibody
This is a rabbit polyclonal antibody against Abca1. It was validated on Western Blot
Target Description: Abca1 is a cAMP-dependent and sulfonylurea-sensitive anion transporter. Abca1 is a key gatekeeper influencing intracellular cholesterol transport.
Product Categories/Family for anti-ABCA1 antibody
Polyclonal; Membrane Protein; Drugs and Drug Metabolism; GPCR;
Applications Tested/Suitable for anti-ABCA1 antibody
Western Blot (WB)
Western Blot (WB) of anti-ABCA1 antibody
WB Suggested Anti-Abca1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Mouse Kidney
NCBI/Uniprot data below describe general gene information for ABCA1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_038482
[Other Products]
NCBI GenBank Nucleotide #
NM_013454
[Other Products]
UniProt Primary Accession #
B1AWZ8
[Other Products]
UniProt Related Accession #
P41233[Other Products]
NCBI Official Full Name
ATP-binding cassette sub-family A member 1
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family A (ABC1), member 1
NCBI Official Symbol
Abca1??[Similar Products]
NCBI Official Synonym Symbols
Abc1; ABC-1
??[Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family A member 1
Protein Family
ABC transporter A family
NCBI Summary for ABCA1
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008]
Research Articles on ABCA1
1. Low ABCA1 expression is associated with atherogenesis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
