Product Name
ANTXR2, Polyclonal Antibody
Full Product Name
ANTXR2 Antibody - N-terminal region
Product Gene Name
anti-ANTXR2 antibody
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Antibody/Peptide Pairs
ANTXR2 peptide (MBS3234810) is used for blocking the activity of ANTXR2 antibody (MBS3209855)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: FSSQATIILP LTGDRGKISK GLEDLKRVSP VGETYIHEGL KLANEQIQKA
3D Structure
ModBase 3D Structure for P58335
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human ANTXR2
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ANTXR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ANTXR2 antibody
This is a rabbit polyclonal antibody against ANTXR2. It was validated on Western Blot
Target Description: This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-ANTXR2 antibody
Polyclonal; Signaling Intermediate; Cell Adhesion; Disease Related;
Applications Tested/Suitable for anti-ANTXR2 antibody
Western Blot (WB)
Western Blot (WB) of anti-ANTXR2 antibody
Host: Rabbit
Target Name: ANTXR2
Sample Type: DU145 Whole cell lysates
Antibody Dilution: 1.0ug/ml
NCBI/Uniprot data below describe general gene information for ANTXR2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001139266.1
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NCBI GenBank Nucleotide #
NM_001145794.1
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UniProt Primary Accession #
P58335
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UniProt Related Accession #
P58335[Other Products]
NCBI Official Full Name
anthrax toxin receptor 2 isoform 2
NCBI Official Synonym Full Names
ANTXR cell adhesion molecule 2
NCBI Official Symbol
ANTXR2??[Similar Products]
NCBI Official Synonym Symbols
HFS; ISH; JHF; CMG2; CMG-2
??[Similar Products]
NCBI Protein Information
anthrax toxin receptor 2
UniProt Protein Name
Anthrax toxin receptor 2
UniProt Synonym Protein Names
Capillary morphogenesis gene 2 protein; CMG-2
Protein Family
Anthrax toxin receptor
UniProt Gene Name
ANTXR2??[Similar Products]
UniProt Synonym Gene Names
CMG2; CMG-2??[Similar Products]
NCBI Summary for ANTXR2
This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
UniProt Comments for ANTXR2
Necessary for cellular interactions with laminin and the extracellular matrix.
Research Articles on ANTXR2
1. this study shows no association between ANTXR2 polymorphisms and ankylosing spondylitis susceptibility in a Chinese Han population, but meta-analysis showed that rs4389526 in the ANTXR2 gene was weakly associated with AS susceptibility in both Caucasian and Chinese Han patients.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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