Human Amiloride-sensitive amine oxidase [copper-containing] (ABP1) ELISA kit; ABP; AOC1; DAO; DAO1; KAO; amiloride binding protein 1; amiloride-binding protein; amiloride-binding protein-1; amiloride-sensitive amine oxidase; diamine oxidase; histaminase; kidney amine oxidase; amiloride binding protein 1 (amine oxidase (copper-containing) )

For Research Use Only. Not for use in diagnostic procedures.

This assay has high sensitivity and excellent specificity for detection of Human ABP1. No significant cross-reactivity or interference between Human ABP1 and analogues was observed.

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of ABP1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS917936 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the amiloride binding protein 1 (amine oxidase (copper-containing) ) (ABP1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ABP1. The ELISA analytical biochemical technique of the MBS917936 kit is based on ABP1 antibody-ABP1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ABP1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ABP1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

85,378 Da

amine oxidase, copper containing 1

amiloride-sensitive amine oxidase [copper-containing]; amiloride-sensitive amine oxidase [copper-containing]; histaminase; diamine oxidase; kidney amine oxidase; amiloride-binding protein 1; amine oxidase copper domain-containing protein 1; amiloride binding protein 1 (amine oxidase (copper-containing))

Amiloride-sensitive amine oxidase [copper-containing]

ABP1; DAO1; DAO; Diamine oxidase; KAO??[Similar Products]

AOC1_HUMAN

This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]

ABP1: Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. Belongs to the copper/topaquinone oxidase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.4.3.22; Oxidoreductase; Secreted, signal peptide; Secreted; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - histidine; Amino Acid Metabolism - arginine and proline

Chromosomal Location of Human Ortholog: 7q36.1

Cellular Component: extracellular space; tight junction; plasma membrane; peroxisome

Molecular Function: amine oxidase activity; heparin binding; copper ion binding; protein homodimerization activity; zinc ion binding; protein complex binding; calcium ion binding; drug binding; cation channel activity; receptor activity; sodium channel activity; quinone binding

Biological Process: response to antibiotic; response to drug; amine metabolic process

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