Product Name
Protein XRP2 (RP2), Recombinant Protein
Full Product Name
Recombinant Chicken Protein XRP2 (RP2)
Product Gene Name
RP2 recombinant protein
[Similar Products]
Product Synonym Gene Name
RP2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-357aa, Full Length of Mature Protein
Sequence
GCFFSKRRKP AQGGQQQGAS QEPAAGEEKA PQYSWDQRAK VDPKDYTFSG LKDETVGRLP GRVAGQQFVI QDCENCSIYI FDHSATVTID DCVNCQIFLG PIKGSVFFRN CKDCKCIVAC QQFRTRDCRR LEVFLCCATQ PIIESSTGMK FGCFQYYYPE LALQFKDAGL SIFNNTWSNI HDFTPVSGEN NWGLLPENAV VQDYVPLPAS EELKAVRVST DAMKSIIPIT RGQRQKNSDE SCLAVFFAGD YTTANARKLI DEMTGKGFQL VQTKEVSMKA EDAQRVFQQC ASEFIPLLER GPVVALEFNG DGAVEGCRNT VNDVFNGTKV FVSESKASAS QDVDNFYNFA DMQMGM
3D Structure
ModBase 3D Structure for Q5ZHN4
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of RP2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
RP2 recombinant protein
The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death
NCBI/Uniprot data below describe general gene information for RP2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001008680.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001008680.1
[Other Products]
UniProt Primary Accession #
Q5ZHN4
[Other Products]
UniProt Related Accession #
Q5ZHN4[Other Products]
Molecular Weight
39,723 Da
NCBI Official Full Name
protein XRP2
NCBI Official Synonym Full Names
retinitis pigmentosa 2 (X-linked recessive)
NCBI Official Symbol
RP2??[Similar Products]
NCBI Protein Information
protein XRP2
UniProt Protein Name
Protein XRP2
UniProt Gene Name
RP2??[Similar Products]
UniProt Comments for RP2
Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as a GTPase-activating protein. May act as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins ().
Research Articles on RP2
1. 26 new mutations in RP2 and RPGR patients with X-linked Retinitis Pigmentosa.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
