Product Name
CACNA2D1, cDNA Clone
Full Product Name
CACNA2D1 cDNA Clone
Product Gene Name
CACNA2D1 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggctgctg gctgcctgct ggccttgact ctgacacttt tccaatcttt gctcatcggc ccctcgtcgg aggagccgtt cccttcggcc gtcactatca aatcatgggt ggataagatg caagaagacc ttgtcacact ggcaaaaaca gcaagtggag tcaatcagct tgttgatatt tatgagaaat atcaagattt gtatactgtg gaaccaaata atgcacgcca gctggtagaa attgcagcca gggatattga gaaacttctg agcaacagat ctaaagccct ggtgcgcctg gcattggaag cggagaaagt tcaagcagct caccagtgga gagaagattt tgcaagcaat gaagttgtct actacaatgc aaaggatgat ctcgatcctg agaaaaatga cagtgagcca ggcagccaga ggataaaacc tgttttcatt gaagatgcta attttggacg acaaatatct tatcagcacg cagcagtcca tattcctact gacatctatg agggctcaac aattgtgtta aatgaactca actggacaag tgccttagat gaagttttca aaaagaatcg cgaggaagac ccttcattat tgtggcaggt ttttggcagt gccactggcc tagctcgata ttatccagct tcaccatggg ttgataatag tagaactcca aataagattg acctttatga tgtacgcaga agaccatggt acatccaagg agctgcatct cctaaagaca tgcttattct ggtggatgtg agtggaagtg ttagtggatt gacacttaaa ctgatccgaa catctgtctc cgaaatgtta gaaaccctct cagatgatga tttcgtgaat gtagcttcat ttaacagcaa tgctcaggat gtaagctgtt ttcagcacct tgtccaagca aatgtaagaa ataaaaaagt gttgaaagac gcggtgaata atatcacagc caaaggaatt acagattata agaagggctt tagttttgct tttgaacagc tgcttaatta taatgtttcc agagcaaact gcaataagat tattatgcta ttcacggatg gaggagaaga gagagcccag gagatattta acaaatacaa taaagataaa aaagtacgtg tattcacgtt ttcagttggt caacacaatt atgacagagg acctattcag tggatggcct gtgaaaacaa aggttattat tatgaaattc cttccattgg tgcaataaga atcaatactc aggaatattt ggatgttttg ggaagaccaa tggttttagc aggagacaaa gctaagcaag tccaatggac aaatgtgtac ctggatgcat tggaactggg acttgtcatt actggaactc ttccggtctt caacataacc ggccaatttg aaaataagac aaacttaaag aaccagctga ttcttggtgt gatgggagta gatgtgtctt tggaagatat taaaagactg acaccacgtt ttacactgtg ccccaatggg tattactttg caatcgatcc taatggttat gttttattac atccaaatct tcagccaaag aaccccaaat ctcaggagcc agtaacattg gatttccttg atgcagagtt agagaatgat attaaagtgg agattcgaaa taagatgatt gatggggaaa gtggagaaaa aacattcaga actctggtta aatctcaaga tgagagatat attgacaaag gaaacaggac atacacatgg acacctgtca atggcacaga ttacagtttg gccttggtat taccaaccta cagtttttac tatataaaag ccaaactaga agagacaata actcaggcca gatcaaaaaa gggcaaaatg aaggattcgg aaaccctgaa gccagataat tttgaagaat ctggctatac attcatagca ccaagagatt actgcaatga cctgaaaata tcggataata acactgaatt tcttttaaat ttcaacgagt ttattgatag aaaaactcca aacaacccat catgtaacgc ggatttgatt aatagagtct tgcttgatgc aggctttaca aatgaacttg tccaaaatta ctggagtaag cagaaaaata tcaagggagt gaaagcacga tttgttgtga ctgatggtgg gattaccaga gtttatccca aagaggctgg agaaaattgg caagaaaacc cagagacata tgaggacagc ttctataaaa ggagcctaga taatgataac tatgttttca ctgctcccta ctttaacaaa agtggacctg gtgcctatga atcgggcatt atggtaagca aagctgtaga aatatatatt caagggaaac ttcttaaacc tgcagttgtt ggaattaaaa ttgatgtaaa ttcctggata gagaatttca ccaaaacctc aatcagagat ccgtgtgctg gtccagtttg tgactgcaaa agaaacagtg acgtaatgga ttgtgtgatt ctggatgatg gtgggtttct tctgatggca aatcatgatg attatactaa tcagattgga agattttttg gagagattga tcccagcttg atgagacacc tggttaatat atcagtttat gcttttaaca aatcttatga ttatcagtca gtatgtgagc ccggtgctgc accaaaacaa ggagcaggac atcgctcagc atatgtgcca tcagtagcag acatattaca aattggctgg tgggccactg ctgctgcctg gtctattcta cagcagtttc tcttgagttt gacctttcca cgactccttg aggcagttga gatggaggat gatgacttca cggcctccct gtccaagcag agctgcatta ctgaacaaac ccagtatttc ttcgataacg acagtaaatc attcagtggt gtattagact gtggaaactg ttccagaatc tttcatggag aaaagcttat gaacaccaac ttaatattca taatggttga gagcaaaggg acatgtccat gtgacacacg actgctcata caagcggagc agacttctga cggtccaaat ccttgtgaca tggttaagca acctagatac cgaaaagggc ctgatgtctg ctttgataac aatgtcttgg aggattatac tgactgtggt ggtgtttctg gattaaatcc ctccctgtgg tatatcattg gaatccagtt tctactactt tggctggtat ctggcagcac acaccgcctg ttatga
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CACNA2D1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CACNA2D1. It may not necessarily be applicable to this product.
NCBI Accession #
BC117468
[Other Products]
UniProt Secondary Accession #
Q17R45; Q9UD80; Q9UD81; Q9UD82[Other Products]
UniProt Related Accession #
P54289[Other Products]
Molecular Weight
122,443 Da
NCBI Official Full Name
Homo sapiens calcium channel, voltage-dependent, alpha 2/delta subunit 1, mRNA
NCBI Official Synonym Full Names
calcium voltage-gated channel auxiliary subunit alpha2delta 1
NCBI Official Symbol
CACNA2D1??[Similar Products]
NCBI Official Synonym Symbols
CACNA2; CCHL2A; CACNL2A; LINC01112; lncRNA-N3
??[Similar Products]
NCBI Protein Information
voltage-dependent calcium channel subunit alpha-2/delta-1
UniProt Protein Name
Voltage-dependent calcium channel subunit alpha-2/delta-1
UniProt Synonym Protein Names
Voltage-gated calcium channel subunit alpha-2/delta-1
Protein Family
Voltage-dependent calcium channel
UniProt Gene Name
CACNA2D1??[Similar Products]
UniProt Synonym Gene Names
CACNL2A; CCHL2A; MHS3??[Similar Products]
UniProt Entry Name
CA2D1_HUMAN
NCBI Summary for CACNA2D1
The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014]
UniProt Comments for CACNA2D1
CACNA2D1: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling. Belongs to the calcium channel subunit alpha-2/delta family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Channel, calcium
Chromosomal Location of Human Ortholog: 7q21-q22
Cellular Component: plasma membrane; voltage-gated calcium channel complex
Molecular Function: voltage-gated calcium channel activity
Biological Process: calcium ion transport; regulation of calcium ion transport
Research Articles on CACNA2D1
1. detected a joint effect of SNP and G x E interaction in BMP2 and CACNA2D1 for depressive state.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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