CLTR1; CYSLT1; CYSLT1R; CYSLTR; cysteinyl leukotriene D4 receptor; cysteinyl leukotriene receptor 1; HG55; HMTMF81; LTD4 receptorCLTR1; CYSLT1; CYSLT1R; CYSLTR; cysteinyl leukotriene D4 receptor; cysteinyl leukotriene receptor 1; HG55; HMTMF81; LTD4 receptor

For Research Use Only. Not for use in diagnostic procedures.

CYSLTR1 antibody detects endogenous levels of total CYSLTR1 protein.

Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Store at-20 degree C for 1 year.

Small volumes of anti-CYSLTR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)

WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:5000

Peptide-+ Western blot analysis of extracts from HeLa cells, HT-29 cells and COLO205 cells, using CYSLTR1 antibody. Immunofluorescence analysis of COS-7 cells, using CYSLTR1 antibody.

38,541 Da

cysteinyl leukotriene receptor 1

cysteinyl leukotriene receptor 1

Cysteinyl leukotriene receptor 1

CYSLT1; CysLTR1; LTD4 receptor??[Similar Products]

This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.

Lynch K.R., Nature 399:789-793(1999). Sarau H.M., Mol. Pharmacol. 56:657-663(1999). Ross M.T., Nature 434:325-337(2005).

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.