Product Name
CHD7, Blocking Peptide
Full Product Name
CHD7 Immunizing Peptide
Product Synonym Names
chromodomain helicase DNA binding protein 7; FLJ20357; FLJ20361; IS3; KIAA1416; Scoliosis, idiopathic 3
Product Gene Name
CHD7 blocking peptide
[Similar Products]
CHD7 peptide (MBS426334) is used for blocking the activity of CHD7 antibody (MBS420342)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
C-KDEIDEFA NSPSE
Species Reactivity
Human, Mouse, Rat
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of CHD7 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CHD7. It may not necessarily be applicable to this product.
NCBI Accession #
NP_060250.2
[Other Products]
NCBI GenBank Nucleotide #
NM_017780.3
[Other Products]
UniProt Secondary Accession #
Q05DI5; Q2TAN4; Q66K35; Q7Z6C0; Q7Z7Q2; Q9NXA0; Q9NXA3; D0VBA5; E9PNZ2[Other Products]
UniProt Related Accession #
Q9P2D1[Other Products]
Molecular Weight
101,085 Da
NCBI Official Full Name
chromodomain-helicase-DNA-binding protein 7 isoform 1
NCBI Official Synonym Full Names
chromodomain helicase DNA binding protein 7
NCBI Official Symbol
CHD7??[Similar Products]
NCBI Official Synonym Symbols
CRG; HH5; IS3; KAL5
??[Similar Products]
NCBI Protein Information
chromodomain-helicase-DNA-binding protein 7
UniProt Protein Name
Chromodomain-helicase-DNA-binding protein 7
UniProt Synonym Protein Names
ATP-dependent helicase CHD7
Protein Family
Chromodomain-helicase-DNA-binding protein
UniProt Gene Name
CHD7??[Similar Products]
UniProt Synonym Gene Names
KIAA1416; CHD-7??[Similar Products]
UniProt Entry Name
CHD7_HUMAN
NCBI Summary for CHD7
This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
UniProt Comments for CHD7
CHD-7: Probable transcription regulator. May interact with CTCF. Interacts with CHD8. Widely expressed in fetal and ***** tissues. Belongs to the SNF2/RAD54 helicase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus; Helicase; DNA-binding; EC 3.6.4.12
Chromosomal Location of Human Ortholog: 8q12.2
Cellular Component: nucleolus; nucleus
Molecular Function: ATP binding; chromatin binding; helicase activity; protein binding
Biological Process: ***** heart development; ***** walking behavior; artery morphogenesis; blood circulation; central nervous system development; chromatin modification; cognition; cranial nerve development; embryonic hindlimb morphogenesis; female genitalia development; genitalia development; heart morphogenesis; in utero embryonic development; inner ear morphogenesis; limb development; nose development; olfactory behavior; olfactory bulb development; olfactory nerve development; palate development; positive regulation of multicellular organism growth; regulation of growth hormone secretion; regulation of neurogenesis; regulation of transcription, DNA-dependent; retina development in camera-type eye; rRNA processing; semicircular canal morphogenesis; sensory perception of sound; skeletal development; T cell differentiation; transcription, DNA-dependent
Disease: Charge Syndrome; Hypogonadotropic Hypogonadism 5 With Or Without Anosmia; Tracheoesophageal Fistula With Or Without Esophageal Atresia
Research Articles on CHD7
1. Here, we review recent work aimed at understanding the mechanism of CHD7 function in normal and pathological states, highlighting results from biochemical and in vivo studies.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
