Product Name
CHD7, Blocking Peptide
Full Product Name
CHD7 Peptide
Product Synonym Names
CRG; HH5; IS3; KAL5; KIAA1416; Chromodomain-helicase-DNA-binding protein 7; ATP-dependent helicase CHD7; CHD-7; chromodomain helicase DNA binding protein 7
Product Gene Name
CHD7 blocking peptide
[Similar Products]
CHD7 peptide (MBS152221) is used for blocking the activity of CHD7 antibody (MBS150915)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9P2D1
Concentration
200 ug/mL (lot specific)
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
17 amino acids near the center of human UHRF1BP1L.
Preparation and Storage
Store CHD7 peptide at -20 degree C, stable for one year.
Other Notes
Small volumes of CHD7 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for CHD7 blocking peptide
Blocking (BL)
Application Notes for CHD7 blocking peptide
CHD7 peptide is used for blocking the activity of CHD7 antibody.
NCBI/Uniprot data below describe general gene information for CHD7. It may not necessarily be applicable to this product.
NCBI Accession #
NP_060250.2
[Other Products]
NCBI GenBank Nucleotide #
NM_017780.3
[Other Products]
UniProt Primary Accession #
Q9P2D1
[Other Products]
UniProt Secondary Accession #
Q05DI5; Q2TAN4; Q66K35; Q7Z6C0; Q7Z7Q2; Q9NXA0; Q9NXA3; D0VBA5; E9PNZ2[Other Products]
UniProt Related Accession #
Q9P2D1[Other Products]
Molecular Weight
101,085 Da
NCBI Official Full Name
chromodomain-helicase-DNA-binding protein 7
NCBI Official Synonym Full Names
chromodomain helicase DNA binding protein 7
NCBI Official Symbol
CHD7??[Similar Products]
NCBI Official Synonym Symbols
CRG; HH5; IS3; KAL5
??[Similar Products]
NCBI Protein Information
chromodomain-helicase-DNA-binding protein 7; CHARGE association; ATP-dependent helicase CHD7; chromodomain helicase DNA binding protein 7 isoform CRA_e
UniProt Protein Name
Chromodomain-helicase-DNA-binding protein 7
UniProt Synonym Protein Names
ATP-dependent helicase CHD7
Protein Family
Chromodomain-helicase-DNA-binding protein
UniProt Gene Name
CHD7??[Similar Products]
UniProt Synonym Gene Names
KIAA1416; CHD-7??[Similar Products]
UniProt Entry Name
CHD7_HUMAN
NCBI Summary for CHD7
This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. [provided by RefSeq, Jul 2008]
UniProt Comments for CHD7
CHD-7: Probable transcription regulator. May interact with CTCF. Interacts with CHD8. Widely expressed in fetal and ***** tissues. Belongs to the SNF2/RAD54 helicase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus; DNA-binding; Helicase; EC 3.6.4.12
Chromosomal Location of Human Ortholog: 8q12.2
Cellular Component: nucleoplasm; nucleolus; nucleus
Molecular Function: protein binding; DNA binding; chromatin binding; helicase activity; ATP binding
Biological Process: limb development; heart morphogenesis; central nervous system development; olfactory behavior; blood circulation; positive regulation of multicellular organism growth; palate development; female genitalia development; ***** walking behavior; olfactory nerve development; embryonic hindlimb morphogenesis; regulation of growth hormone secretion; sensory perception of sound; regulation of neurogenesis; regulation of transcription, DNA-dependent; skeletal development; T cell differentiation; ***** heart development; inner ear morphogenesis; transcription, DNA-dependent; in utero embryonic development; olfactory bulb development; semicircular canal morphogenesis; cranial nerve development; chromatin modification; genitalia development; retina development in camera-type eye; artery morphogenesis; cognition; nose development; rRNA processing
Disease: Charge Syndrome; Tracheoesophageal Fistula With Or Without Esophageal Atresia; Hypogonadotropic Hypogonadism 5 With Or Without Anosmia
Research Articles on CHD7
1. The objective of the study was to determine the nature, prevalence, mode of transmission, and clinical spectrum of CHD7 mutations in a large series of patients.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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