Mouse Transcriptional regulator ATRX (ATRX) ELISA kit; RP5-875J14.1; ATR2; MGC2094; MRXHF1; RAD54; RAD54L; SFM1; SHS; XH2; XNP; ZNF-HX; DNA dependent ATPase and helicase; X-linked nuclear protein; Zinc finger helicase; helicase 2; X-linked; transcriptional; alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog; S. cerevisiae)

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of ATRX elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9330980 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) (ATRX) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ATRX. The ELISA analytical biochemical technique of the MBS9330980 kit is based on ATRX antibody-ATRX antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ATRX antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ATRX. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

278,587 Da

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

transcriptional regulator ATRX; X-linked nuclear protein; heterochromatin protein 2; ATP-dependent helicase ATRX; HP1 alpha-interacting protein; alpha thalassemia/mental retardation syndrome (X-linked)

Transcriptional regulator ATRX

Hp1bp2; Xnp??[Similar Products]

ATRX_MOUSE

ATRX: a global transcriptional regulator. Belongs to the SNF2 family of proteins, many of which modify gene expression via chromatin remodeling activity. Involved in the developmental silencing of imprinted genes in the brain. Contains one PxVxL motif, which is required for interaction with chromoshadow domains. This motif requires additional residues at -7, -6, +4 and +5 relative to the central V which contact the chromoshadow domain. Constitutive mutations in ATRX are associated with brain, facial, and genital abnormalities, and alpha thalassemia. Acquired mutations in ATRX have been observed in preleukemic conditions. Six alternatively spliced human isoforms have been described.

Protein type: Ubiquitin conjugating system; DNA repair, damage; EC 3.6.4.12; Helicase

Cellular Component: nucleoplasm; nuclear chromosome; heterochromatin; chromosome, telomeric region; cytoplasm; chromosome; intracellular; nucleus

Molecular Function: protein binding; DNA binding; hydrolase activity; histone binding; zinc ion binding; metal ion binding; nucleotide binding; chromatin binding; DNA translocase activity; helicase activity; methylated histone residue binding; ATP binding

Biological Process: transcription, DNA-dependent; DNA damage response, signal transduction by p53 class mediator; multicellular organism growth; positive regulation of telomere maintenance; chromatin modification; DNA repair; Sertoli cell development; replication fork processing; chromatin remodeling; nucleosome assembly; regulation of transcription, DNA-dependent; DNA replication-independent nucleosome assembly; post-embryonic forelimb morphogenesis; forebrain development; positive regulation of transcription from RNA polymerase II promoter; spermatogenesis; response to DNA damage stimulus

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.