Product Name
Chromodomain-helicase-DNA-binding protein 7 (Chd7), Recombinant Protein
Full Product Name
Recombinant Mouse Chromodomain-helicase-DNA-binding protein 7 (Chd7) , partial
Product Gene Name
Chd7 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
708-970; Partial.
Sequence
KTEGSENSDL DKTPPPSPAP EEDEDPGVQK RRSSRQVKRK RYTEDLEFKI SDEEA DDADAAGRDS PSNTSQSEQQ ESVDAEGPVV EKIMSSRLVK KQKESGEEVE VEEF YVKYKNFSYL HCQWASVEDL EKDKRIQQKI KRFKSKQGQS KFLSEIEDDL FNPDYV EVDRIMDFAR STDDRGEPVI HYLVKWCSLP YEDSTWELKQ DIDQTKIEEF EKLMSR EPETERVERP PADDWKKSES SREYKNNNKL REYQLEGVNW LL
3D Structure
ModBase 3D Structure for A2AJK6
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Chd7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Chd7 recombinant protein
This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome.
NCBI/Uniprot data below describe general gene information for Chd7. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001264078.1
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NCBI GenBank Nucleotide #
NM_001277149.1
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UniProt Primary Accession #
A2AJK6
[Other Products]
UniProt Secondary Accession #
Q3TA86; Q3TAG7; Q3TBU4; Q8C986; Q8K244[Other Products]
UniProt Related Accession #
A2AJK6[Other Products]
Molecular Weight
331,195 Da
NCBI Official Full Name
chromodomain-helicase-DNA-binding protein 7 isoform 1
NCBI Official Synonym Full Names
chromodomain helicase DNA binding protein 7
NCBI Official Symbol
Chd7??[Similar Products]
NCBI Official Synonym Symbols
Dz; Mt; Cyn; Edy; Flo; Lda; Obt; Whi; Cycn; Todo; WBE1; metis; GENA 47; GENA 60; Gena 52; A730019I05Rik
??[Similar Products]
NCBI Protein Information
chromodomain-helicase-DNA-binding protein 7
UniProt Protein Name
Chromodomain-helicase-DNA-binding protein 7
UniProt Synonym Protein Names
ATP-dependent helicase CHD7
Protein Family
Chromodomain-helicase-DNA-binding protein
UniProt Gene Name
Chd7??[Similar Products]
UniProt Synonym Gene Names
CHD-7??[Similar Products]
NCBI Summary for Chd7
This gene encodes a protein containing two chromodomains and an ATP-binding helicase domain that functions as a regulator of transcription. Mutations in this gene result in an array of development defects, including inner ear problems. Mice defective for this gene exhibit many of the clinical features of the CHARGE syndrome caused by mutations in the homologous gene in human. [provided by RefSeq, Sep 2015]
UniProt Comments for Chd7
Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production ().
Research Articles on Chd7
1. Chd7 deficiency delays leukemia initiation induced by Cbfb-MYH11.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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