Product Name
GnRH I, Polyclonal Antibody
Full Product Name
GnRH I Antibody
Product Synonym Names
GNRH1; Gonadoliberin; LHRH; LNRH; GnRH-associated peptide 1; Progonadoliberin-1; Progonadoliberin I; Luliberin I; GNRH; GRH; HH12
Product Gene Name
anti-GnRH I antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P01148
Specificity
GnRH I Antibody detects endogenous levels of total GnRH I
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (lot specific)
Immunogen
A synthesized peptide derived from human GnRH I
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-GnRH I antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-GnRH I antibody
Total protein Ab
Applications Tested/Suitable for anti-GnRH I antibody
Western Blot (WB)
Application Notes for anti-GnRH I antibody
Western Blot: 1:1000-3000
Western Blot (WB) of anti-GnRH I antibody
Western blot analysis GnRH I using COS7 whole cell lysates
NCBI/Uniprot data below describe general gene information for GnRH I. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001076580.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001083111.1
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UniProt Primary Accession #
P01148
[Other Products]
UniProt Secondary Accession #
A0AVP0[Other Products]
UniProt Related Accession #
P01148[Other Products]
Molecular Weight
10,380 Da
NCBI Official Full Name
progonadoliberin-1 isoform 2 preproprotein
NCBI Official Synonym Full Names
gonadotropin releasing hormone 1
NCBI Official Symbol
GNRH1??[Similar Products]
NCBI Official Synonym Symbols
GRH; GNRH; LHRH; LNRH
??[Similar Products]
NCBI Protein Information
progonadoliberin-1
UniProt Protein Name
Progonadoliberin-1
UniProt Synonym Protein Names
Progonadoliberin I
UniProt Gene Name
GNRH1??[Similar Products]
UniProt Synonym Gene Names
GNRH; GRH; LHRH; GnRH-I; LH-RH I??[Similar Products]
UniProt Entry Name
GON1_HUMAN
NCBI Summary for GnRH I
This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015]
UniProt Comments for GnRH I
GNRH1: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones. Belongs to the GnRH family.
Protein type: Cell cycle regulation; Hormone; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 8p21-p11.2
Cellular Component: extracellular region
Molecular Function: hormone activity
Biological Process: cell-cell signaling; multicellular organismal development; negative regulation of cell proliferation; signal transduction
Disease: Hypogonadotropic Hypogonadism 7 With Or Without Anosmia
Research Articles on GnRH I
1. mutations in the region encoding the decapeptide associated with complete Idiopathic hypogonadotropic hypogonadism
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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