Product Name
ADAMTS-like protein 4 (ADAMTSL4), Recombinant Protein
Full Product Name
Recombinant Human ADAMTS-like protein 4 (ADAMTSL4) , partial
Product Gene Name
ADAMTSL4 recombinant protein
[Similar Products]
Product Synonym Gene Name
ADAMTSL4[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q6UY14
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ADAMTSL4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ADAMTSL4 recombinant protein
This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse
biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
NCBI/Uniprot data below describe general gene information for ADAMTSL4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001275536.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001288607.1
[Other Products]
UniProt Primary Accession #
Q6UY14
[Other Products]
UniProt Secondary Accession #
Q5T5F7; Q6IPM6; Q8N643; Q9HBS6; B2RTT0; F8WAD0[Other Products]
UniProt Related Accession #
Q6UY14[Other Products]
Molecular Weight
118,822 Da
NCBI Official Full Name
ADAMTS-like protein 4 isoform 3
NCBI Official Synonym Full Names
ADAMTS like 4
NCBI Official Symbol
ADAMTSL4??[Similar Products]
NCBI Official Synonym Symbols
TSRC1; ECTOL2; ADAMTSL-4
??[Similar Products]
NCBI Protein Information
ADAMTS-like protein 4
UniProt Protein Name
ADAMTS-like protein 4
UniProt Synonym Protein Names
Thrombospondin repeat-containing protein 1
Protein Family
ADAMTS-like protein
UniProt Gene Name
ADAMTSL4??[Similar Products]
UniProt Synonym Gene Names
; ADAMTSL-4??[Similar Products]
NCBI Summary for ADAMTSL4
This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Sep 2014]
UniProt Comments for ADAMTSL4
Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis.
Research Articles on ADAMTSL4
1. A recurrent pathogenic ADAMTSL4 variant is a major cause of early onset autosomal recessive ectopia lentis in a Cook Island Maori population and associated with a common haplotype, suggesting a founder effect.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.